Research Fellow in Quantitative Interaction Proteomics and Chemoproteomics

The Faculty of Organic Sciences at Queen’s College Belfast, is at present in search of to recruit a gifted Analysis Fellow in Quantitative Interplay Proteomics and Chemoproteomics.

An skilled and motivated postdoctoral scientist is sought to affix the Collins Lab (https://collinslab.internet/ ) within the Faculty of Organic Sciences at Queen’s College Belfast. The profitable candidate will undertake a senior function within the planning and supply of analysis exercise targeted on quantitative interplay proteomics and information unbiased acquisition (DIA) mass spectrometry.

Our analysis group focuses on (i) improvement of latest methodology in DIA mass spectrometry1,2 , (ii) strategies to characterize dynamic reorganization of protein complexes/interactions utilizing each focused and world approaches3,4 , and most lately (iii) the applying of those strategies in chemical biology and drug discovery, and (iv) the applying of those strategies to issues in varied illness settings together with innate immunity, most cancers, and host-pathogen interactions. This function will concentrate on the event and utility of methods to quantify protein complicated reorganization in signalling techniques. It will embody of neo protein-protein interactions by chemical induced proximity related within the context of early-stage drug discovery.

The profitable candidate may have a demonstrated observe report in mass spectrometry-based proteomics analysis with a superb PhD diploma awarded and robust publication report. The profitable candidates may have obligations in unbiased analysis, supervision, planning, day-to-day lab administration, collaborations, and outreach. The function will embody entry to newly established functionality throughout the new Chemoproteomics Centre of Excellence located inside QUB (https://bit.ly/chemoprot ).

References: 1 Meier, F. et al.Nature Strategies 17, 1229 (2020) 2 Collins, B. C. et al.Nature Communications 8, 291 (2017) 3 Collins, B. C. et al.Nat Meth 10, 1246 (2013) 4 Heusel, M. et al.Cell Programs 10, 133 (2020).

The profitable candidate should have, and your utility ought to clearly exhibit that you simply meet the next standards:

Have or about to acquire* a PhD in quantitative proteomics, mass spectrometry, or a associated self-discipline. (* inside 3 months of graduation of publish).

Substantial related analysis expertise in creating and making use of mass spectrometry-based quantitative proteomics strategies.

Peer reviewed publications or preprints within the space of mass spectrometry-based proteomics.

Expertise within the common upkeep and technical troubleshooting of mass spectrometry devices.

Expertise in pattern preparation and separations for mass spectrometry-based proteomics.

Sensible expertise in processing, recording and dealing with information units, and performing statistical evaluation.

Sturdy publication report in peer reviewed journals.

Expertise with information evaluation utilizing scripting (e.g. R, python, unix).

Please word the above will not be an exhaustive record. For additional details about the function together with the important and fascinating standards please click on on the Candidate Data.

This can be a fastened time period publish accessible for 21 months (anticipated begin by 1 June 2024. Fastened time period contract posts can be found for the acknowledged interval within the first occasion however particularly circumstances could also be renewed or made everlasting topic to availability of funding.

At Queen’s our individuals are on the coronary heart of all the pieces we do. As a employees member you’ll turn out to be a part of a vibrant organisational tradition, which can give you the chance to attain your full potential and improve your profession via a steady concentrate on studying and improvement.

We provide a superb employment package deal that features:

• Nice phrases & situations
• Pension schemes
• Versatile working by enabling you to design your working week in collaboration together with your supervisor via a mix of distant and workplace working
• Household-friendly initiatives
• Profession improvement alternatives
• Assist for well being & psychological wellbeing
• Beneficiant vacation entitlement of 8.4 weeks a 12 months (made up of 23 days annual depart, 10 closure days and 9 financial institution holidays)

Queen’s College is dedicated to selling equality of alternative to all. We’ve created an inclusive tradition by establishing employees networks similar to iRise (Black, Asian, Minority Ethnic and Worldwide Workers Community) and PRISM (LGBTQ+) which assist us progress equality.

We additionally subscribe to Equality Constitution Marks such because the Variety Constitution Mark NI along with Athena Swan. For additional data on our dedication to Equality, Variety and Inclusion, please go to:  www.qub.ac.uk/range ; www.qub.ac.uk/qgi  and www.qub.ac.uk/websites/StaffGateway/StaffNetworks/

Casual enquiries could also be directed to Mohammad Arefian at [email protected]

Candidate Data

In regards to the Faculty

Engaging Reward Bundle

Data for Worldwide Candidates