Research Associate

Job Description

That is an thrilling alternative to affix an internationally main interdisciplinary workforce of King’s Faculty London, Oxford College and Surrey College scientists engaged on the ‘Thoughts & Pores and skin’ analysis programme.

Funded by the UK Medical Analysis Basis, we’re producing advanced sleep monitoring, mind imaging and pores and skin phenotyping information to grasp the mechanisms underpinning adolescent pores and skin issues. We are going to make use of machine studying, synthetic intelligence and information integration approaches to check potential hyperlinks between atopic dermatitis (AD), pruritus, sleep disturbance and altered mind operate, together with cognitive adjustments.

The bioinformatician will work underneath the supervision of Dr. Alessandra Vigilante, Senior Lecturer in Bioinformatics, and Professor Carsten Flohr, Chair in Dermatology and Inhabitants Well being Science and Thoughts & Pores and skin Chief Investigator and be embedded within the new KCL Hub for Utilized Bioinformatics (HAB). S/he’ll present assist within the information integration analyses in addition to statistical evaluation of information. The primary function of the function encompasses performing information integration and statistical evaluation whereas providing complete data-driven choice assist by overseeing the cleansing, integration, and evaluation of numerous datasets, together with pores and skin microbiome, pores and skin immune profiles, sleep measurements, and MRI imaging. This crucially includes collaborating intently with the interdisciplinary workforce to make sure the harmonization and cleanliness of a number of datasets, with the last word purpose of uncovering connections between adolescent pores and skin issues, sleep disruptions, and altered mind operate within the ‘Thoughts & Pores and skin’ analysis programme.

We search for an bold candidate with established experience in bioinformatics, particularly coping with giant information units and information integration. Information of python and R are important.

Additional details about the Thoughts & Pores and skin challenge is discovered right here:

https://onlinelibrary.wiley.com/doi/10.1111/all.15818

For extra details about the put up, please contact Alessandra Vigilante ( [email protected] ) and Carsten Flohr ( [email protected]) ).

Concerning the College:

King’s Faculty London College of Life Sciences and Drugs is among the largest and most profitable centres for analysis and schooling within the College. It consists of over 2000 workers and 5000 college students inside seven Faculties and two Faculties of Training.

The FoLSM Utilized Bioinformatics Hub, house of a brand new and interdisciplinary community, is positioned on the Man’s Campus in central London. It acts as a nucleus for a vibrant analysis neighborhood spanning the whole College, bringing collectively researchers concerned in numerous analysis areas equivalent to computational genomics, genetics, most cancers genomics, dermatology, immunology, reproductive biology and little one well being, cardiovascular analysis, neurobiology, evolutionary biology, pharmacology and others.

Hub for Utilized Bioinformatics (HAB)

https://www.kcl.ac.uk/analysis/the-hub-for-applied-bioinformatics-hab 

That is an interdisciplinary cross-cutting community that brings collectively teachers, clinicians and workers with totally different experience and necessities, to assist and undertake ground-breaking analysis involving large information, and ship high-level education schemes. It acts as a nucleus for a vibrant analysis neighborhood, spanning the whole College of Life Science and Drugs.

This put up might be supplied on a fixed-term contract for twenty-four Months.

It is a full-time put up – 100% full time equal.

Key Obligations

• Present bioinformatics experience to assist the Thoughts & Pores and skin programme members to realize the analysis aims.
• Information and statistical evaluation
• Dataset integration
• Information administration
• Maintain a superb document of research
• Put together and current information to colleagues and different scientists
• Contribute to the manufacturing of analysis experiences and publications
• The put up holder could also be requested to contribute bioinformatics experience to different tasks led by Professor Carsten Flohr.

The above checklist of duties will not be exhaustive, and the put up holder might be required to undertake such duties and duties as might fairly be anticipated inside the scope and grading of the put up.

Abilities, information, and expertise

Important standards

A PhD in Bioinformatics, Computational Biology, Biostatistics, or a associated subject.

Demonstrated experience in dealing with and analyzing large-scale organic datasets.

Proficiency in programming languages generally utilized in bioinformatics, notably Python and R.

Expertise with information integration strategies, together with however not restricted to machine studying algorithms, synthetic intelligence strategies, and statistical approaches.

Sturdy statistical evaluation expertise and familiarity with related software program packages for information evaluation and visualization.

Means to work collaboratively in an interdisciplinary analysis atmosphere, successfully speaking advanced technical ideas to non-technical workforce members.

Wonderful problem-solving expertise and a spotlight to element, with the power to troubleshoot and optimize bioinformatics workflows.

Demonstrated potential to handle and prioritize a number of duties successfully.

Sturdy written and verbal communication expertise, evidenced by the power to write down scientific experiences, manuscripts, and grant purposes

Fascinating standards

Earlier expertise in analyzing sleep monitoring information, mind imaging information, or microbiome and phenotypic information associated to pores and skin issues.

Information of information administration finest practices, together with information versioning, documentation, and reproducibility.

Prior involvement in interdisciplinary analysis collaborations, notably within the fields of dermatology, neuroscience, or sleep medication.

Proof of unbiased analysis initiative, equivalent to publications in peer-reviewed journals or contributions to open-source bioinformatics software program tasks.

* Please observe that this can be a PhD stage function however candidates who’ve submitted their thesis and are awaiting award of their PhDs might be thought-about. In these circumstances the appointment might be made at Grade 5, backbone level 30 with the title of Analysis Assistant. Upon affirmation of the award of the PhD, the job title will change into Analysis Affiliate and the wage will enhance to Grade 6.