NATA Chemistry Research Scientist

Band: MRC – 4

Location: Harwell Campus, Oxfordshire

Wage: £39,375 – £41,843

Contract Sort: Everlasting

Job Sort: Science

Full Time / Half Time: Full Time

The Function

That is an thrilling function in a dynamic and rising interdisciplinary crew on the NATA Hub growing new therapeutic oligonucleotides for numerous translational and collaborative initiatives. The Analysis Scientist will play a key function in designing, synthesising, and evaluating present and new chemical modifications for nucleic acid therapeutics. As well as, the Analysis Scientist will design and implement processes and workflows for nucleic acid synthesis, purification, and scale-up.

Foremost Tasks

• Work intently with colleagues to carry out the design, synthesis, and analysis of oligonucleotides.
• Design and implement processes and workflows for the manufacturing of oligonucleotides.
• Take a proactive strategy to studying and implementing new methods and strategies associated to oligonucleotide improvement.
• Carry out HPLC purification of oligonucleotides and associated biomolecules.
• Handle devices, reagents, and chemical assets effectively.
• Troubleshoot and upkeep of procedures and instrumentation.
• Put together knowledge sheets and reviews.
• Maintain glorious scientific data and implement databases.
• Preserve data of the related literature.
• Recognise alternatives for the creation of mental property and cooperate in patent safety and exploitation.
• Current work internally and contribute to lab conferences.

Different Tasks

• Help the Lab Supervisor in enterprise lab administration duties akin to lab and tools upkeep, well being and security administration, reagent stock and related databases.
• Help high quality management duties when obligatory
• Attend related conferences and conferences.
• Undertake any obligatory coaching that contributes to the event of the principle tasks.

Particular person Specification

Important Choice Standards

• Maintain a PhD in a biochemistry-related subject or equal analysis/trade expertise.
• Expertise working with analytical methods of biomolecules, ideally nucleic acids.
• Primary data in nucleic acid bioinformatics
• Data in oligonucleotide synthesis
• Expertise in knowledge evaluation and interpretation
• Data in HPLC purification programs
• Interdisciplinary pursuits with an emphasis on in vitro and in vivo testing
• Glorious communication abilities and efficient engagement with colleagues and collaborators
• Excessive degree of motivation and drive with the flexibility to multi-task and prioritise work successfully.
• Self-discipline and regard for knowledge integrity, confidentiality, and safety
• Willingness to study.
• Capability to put in writing scientifically.
• Able to crucial pondering
• Working and adhering to straightforward working procedures and expertise in course of evaluation and refinement
• Organised, hard-working with a powerful eye for element and talent to work as a part of a crew.
• Versatile and adaptable, in a position to handle to alter priorities.
• Laptop literacy is important for the recording and communication of outcomes.
• Capability to work to deadlines and meet milestones.
• Good time administration and punctuality

Fascinating choice standards

• Primary data in molecular biology
• Excessive degree of laptop literacy
• Expertise in GMP/GLP and high quality programs
• Expertise within the synthesis of fluorescent-labelled oligonucleotides
• Expertise in massive knowledge set evaluation and database administration

The MRC is a good place to work and progress your profession, be it in scientific analysis or the help capabilities.The MRC is a novel working atmosphere the place our researchers are rewarded by world class innovation and collaboration alternatives that the MRC title brings. The MRC is a superb place to develop your self additional and a variety of coaching & improvement alternatives will likely be obtainable to you, together with skilled registration with the Science Council.

Selecting to return to work on the MRC (a part of UKRI) signifies that you should have entry to an entire host of advantages from an outlined profit pension scheme and glorious vacation entitlement to entry to worker buying/journey reductions and wage sacrifice cycle to work scheme, in addition to the possibility to place the MRC and UKRI in your CV sooner or later.

Our success depends upon our capability to embrace variety and draw on the talents, understanding and expertise of all our folks. We welcome functions from all sections of the neighborhood regardless of gender, race, ethnic or nationwide origin, faith or perception, sexual orientation, incapacity or age. As “Incapacity Assured” employers, we assure to interview all candidates with disabilities who meet the minimal standards for the emptiness.

UKRI helps analysis in areas that embody animal well being, agriculture and meals safety, and bioscience for well being which incorporates analysis on animals, genetic modification and stem cell analysis. While chances are you’ll not have direct involvement in one of these analysis, it’s best to contemplate whether or not this conflicts together with your private values or beliefs.

We’ll conduct a full and complete pre-employment examine as a vital a part of the recruitment course of on all people which might be supplied a place with UKRI. This may embody a safety examine and an excessive organisations affiliation examine.  The function holder will likely be required to have the suitable degree of safety screening/vetting required for the function.  UKRI reserves the correct to run or re-run safety clearance as required throughout the course of employment.