Sr. Scientist, Molecular Discovery

Job title:

Sr. Scientist, Molecular Discovery

Company

MSD

Job description

Job DescriptionOur company has a rapidly growing interdisciplinary team of scientists in London and exciting plans to expand our London presence, initially at The Francis Crick Institute as part of our ‘Skylab’ expansion, and from 2027 in our new state-of-the-art London Discovery Research Centre and UK Headquarters at the hub of London’s Knowledge Quarter. This will be home to approximately 180 scientists alongside other colleagues in clinical, regulatory and business roles, including marketing, finance and administration.Role Overview:We are looking for a laboratory-based Senior Scientist, with exceptional wet lab skills, to help shape our company’s new London Discovery Biologics team at The Francis Crick Institute. Our aim is to discover, and develop, novel therapeutics in the field of immunology and neuroscience.You will be part of a new multi-disciplinary team generating antibodies to support new drug candidate discovery and development. As a laboratory based scientist, you will be responsible for key aspects in the identification, expression, purification, engineering and characterisation of pre-clinical candidate molecules. The role is a key interface with immunology, neuroscience and other functions across our company, as well as with external academic and industrial partners.When submitting your application, please highlight your relevant antibody expertise.What you will need to be successful in this role:

• Exceptional wet-lab and excellent communication skills.

• A high level of independent motivation and a strong team work ethic.

• Ability to deliver to tight timelines and work effectively across departments and multi-disciplinary teams.

• Passion for innovation and problem-solving.

• Good organisational, time management and record keeping skills.

• Ability to adapt to changing priorities.
• We recognise that the diversity in our team is our strength and are committed to creating an inclusive environment for all employees. Successful candidates must demonstrate inclusive behaviours in working with a diverse group of scientists to drive our core mission.

Responsibilities:

• Unique opportunity to help build and shape the new Discovery Biologics laboratory.

• Proactively drive antibody projects from the laboratory.

• Design, plan and execute experiments and analyse data independently, demonstrating scientific rigor and critical thinking.

• Document protocols and data in electronic laboratory notebooks and internal biological registration system.

• Report and disseminate data to project teams.

• Present experimental data at cross-functional meetings.

Required Experience:

• PhD in Biochemistry / Immunology / Neuroscience / Molecular Biology (or related field), or a M.Sc. and a minimum of 5+ years industry experience, or a B.Sc. with 8+ years of industry experience.
• Excellent communication skills and collaborative mindset with ability to work and share knowledge across disciplines and departments.

Preferred experience:

• Relevant pharmaceutical industry experience highly preferred.

Working knowledge in some of the following areas:

• Antibody structure/function/novel formats.
• Practical experience with analytical assays for characterisation, and biophysical understanding of proteins/antibodies (e.g. LC/MS, SPR).
• Cell culture – protein expression and purification (e.g. Affinity chromatography, IEX, HIC, SEC, AKTA).
• Molecular biology (e.g. PCR, cloning and mutagenesis).
• Antibody sequence optimisation and engineering.
• Outsourcing and working with CROs.
• High-dimensional flow cytometry and FACS-based immunophenotyping (both panel design and downstream data analysis).
• Protein design/engineering (structure-based, AI-guided).
• Operating automation (e.g. liquid handling).

What we will offer you:An excellent opportunity to join a leading biopharmaceutical company and help establish the new London Discovery Biologics team.Your role at our company is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At our company, we’re inventing for life.We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively for the common good. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.This role requires full-time presence in the lab, onsite at The Francis Crick Institute in Central London.Closing date for applications: 20th January 2025Current Employees applyCurrent Contingent Workers applySearch Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.Employee Status: RegularRelocation:VISA Sponsorship:Travel Requirements:Flexible Work Arrangements: Not ApplicableShift:Valid Driving License:Hazardous Material(s):Job Posting End Date: 01/21/2025*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Expected salary

Location

London

Job date

Sun, 22 Dec 2024 02:56:58 GMT

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