Bioproducing a weight loss fibre product from algal waste (Bioproducing a weight loss fibre product from algal waste (TODD_U25CASE))

Primary Supervisor – Professor Jonathan Todd 

Introduction: 

Demand for natural weight loss remedies is exceptionally high. With Central Pharma Biotechnica Limited (Biotechnica), this PhD aims to develop a cost-effective and low carbon emission, microbial route to bioproduce a high-value weight loss fibre product from seaweed waste. Currently, our seaweed-derived fibre contains sulfur molecules that confer it bad tastes and smells. Microbial fermentation is our chosen route to safely remove these compounds. Our product would enhance the seaweed industry and offer natural and safe routes to weight loss and fibre provision. This PhD provides multidisciplinary training, the environment and award-winning pilot work for the student to build upon and develop/optimise our unique Intellectual Property (IP) for industry. Additionally, the successful applicant will conduct an industrial placement at Biotechnica.  

Methodology: 

You will be trained in molecular microbiology to isolate and/or genetically manipulate proprietary microbial strains that remove sulfur compounds present in seaweed-derived fibres. You will learn analytical chemistry techniques, e.g. nuclear magnetic resonance spectroscopy and gas chromatography, to monitor sulfur compound removal. You will investigate growth conditions in batch and ultimately in bioreactor settings that optimise sulfur compound removal by the strains you generate but which retain the beneficial fibre properties. Finally, throughout the PhD, you will be encouraged to interact with industry to explore routes to market for the IP you develop.  

Training: 

You will receive exceptional training at UEA and Biotechnica in molecular biology, fermentation, analytical and organic chemistry, coastal fieldwork, industrial networking and in writing publications and IP protection. You will learn good laboratory and manufacturing practices, present your findings at weekly team meetings, high-profile international scientific conferences, write peer-reviewed scientific publications and your PhD thesis. 

Person specification:  

We require a committed, pro-active, and self-reliant student keen to master a wide range of techniques. Experience in some of the key components is desirable. 

The Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP) is offering fully funded studentships for October 2025 entry. The programme offers postgraduates the opportunity to undertake a 4-year PhD research project whilst enhancing professional development and research skills through a comprehensive training programme. You will join a vibrant community of world-leading researchers. All NRPDTP CASE students undertake a three to 18-month placement with the non-academic partner during their study. The placement offers experience designed to enhance professional development. Full support and advice will be provided by our Professional Internship team. Students with, or expecting to attain, at least an upper second-class honours degree, or equivalent, are invited to apply. 

This project has been shortlisted for funding by the NRPDTP. Shortlisted applicants will be interviewed on 28, 29 or 30 January 2025.  

Visit our website for further information on eligibility and how to apply: https://biodtp.norwichresearchpark.ac.uk/ 

Our partners value diverse and inclusive work environments that are positive and supportive. Students are selected for admission without regard to gender, marital or civil partnership status, disability, race, nationality, ethnic origin, religion or belief, sexual orientation, age or social background. 

 Entry requirements

At least UK equivalence Bachelors (Honours) 2:1 or UK equivalence Master’s degree. English Language requirement (Faculty of Science equivalent: IELTS 6.5 overall, 6 in each category). 

Mode of study

Full time

Start date

1 October 2025