Building Enzymes with New Catalytic Functions & Design and Evolution of Enzymes with New Catalytic Functions

A fully funded studentship is available, based at the Manchester Institute of Biotechnology under the supervision of Prof Anthony Green.

The design of enzymes with new modes of catalysis is a major objective in modern biocatalysis. In this project will use state-of-the-art enzyme design, engineering and characterization technologies to develop enzymes for valuable chemical transformations that are unknown in nature. These enzymes will then be used as biocatalysts for the efficient, selective and sustainable production of new bioactive molecules of interest to our industry partners from across the pharmaceutical sector.

The project is highly interdisciplinary at the cutting edge of enzyme design and engineering research. The successful applicants will have full access to state-of-the-art facilities for high-throughput and automated enzyme engineering, including liquid handling robots, colony pickers and a suite of high throughput analytical facilities. The project is supported by several major industry partners, providing the student with opportunities to work across both fundamental and translational science. 

Eligibility

Applicants should have, or expect to achieve, at least a 2.1 honours degree or a master’s in chemistry, biochemistry or a related discipline.

Funding

At Manchester we offer a range of scholarships, studentships and awards at university, faculty and department level, to support both UK and overseas postgraduate researchers.

For more information, visit our funding page or search our funding database for specific scholarships, studentships and awards you may be eligible for.

Before you apply

We strongly recommend that you contact the supervisor for this project before you apply.

How to apply

To be considered for this project you’ll need to complete a formal application through our online application portal.

When applying, you’ll need to specify the full name of this project, the name of your supervisor, how you’re planning on funding your research, details of your previous study, and names and contact details of two referees.

Your application will not be processed without all of the required documents submitted at the time of application, and we cannot accept responsibility for late or missed deadlines. Incomplete applications will not be considered.

If you have any questions about making an application, please contact our admissions team by emailing [email protected].

Equality, diversity and inclusion is fundamental to the success of The University of Manchester, and is at the heart of all of our activities. We know that diversity strengthens our research community, leading to enhanced research creativity, productivity and quality, and societal and economic impact.

We actively encourage applicants from diverse career paths and backgrounds and from all sections of the community, regardless of age, disability, ethnicity, gender, gender expression, sexual orientation and transgender status.

We also support applications from those returning from a career break or other roles. We consider offering flexible study arrangements (including part-time: 50%, 60% or 80%, depending on the project/funder).

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