Clinical Research Fellow

Job title:

Scientific Analysis Fellow

Firm

British Medical Journal

Job description

The UCL Huntington’s Illness Centre is uniquely positioned world-wide to translate mechanistic insights to ‘first in human’ research. It combines refined cell-based techniques with rigorously standardised preclinical goal validation to prime mechanistically-driven drug growth initiatives. The Centre integrates scientific and laboratory work with small proof-of-concept first in human research in sufferers within the Leonard Wolfson Experimental Neurology Centre (LWENC) previous to initiating bigger part 2 and three scientific trials together with novel huntingtin-lowering trials.We’re recruiting a Scientific Analysis Fellow to affix the Centre to work on the Deal with-HD challenge, an revolutionary research funded by Wellcome and led by Professor Sarah J Tabrizi, that seeks to additional perceive neurodegeneration utilizing HD as a mannequin dysfunction. That is an thrilling alternative to affix a world main analysis group who’re main the best way in creating and testing novel therapies for HD sufferers. We have now sturdy partnerships with biotech and pharmaceutical corporations in addition to collaborations with quite a few worldwide tutorial analysis teams.You’ll primarily drive the scientific goals of our HD Younger Grownup Research (HD-YAS): to find out early systems-level pathology and influence on symptomatology in younger grownup HD gene carriers and to establish goal engagement and efficacy markers for future therapeutic trials.This key submit inside Professor Tabrizi’s crew will present distinctive analysis and scientific expertise in neurogenetics, neurodegenerative illnesses, Huntington’s illness, motion problems, 3T and 7T neuroimaging, CSF biology and biomarkers and cognitive neuroscience.Additionally, you will have the chance to grow to be concerned within the early part gene remedy and antisense oligonucleotide remedy trials ongoing in HD. You may be an integral a part of the HD Analysis Centre, taking part within the multidisciplinary HD and neurogenetics clinics on the NHNN, underneath the scientific supervision of Professors Sarah Tabrizi and Edward Wild. You should have the prospect to check for the next diploma, benefitting from tutorial help from world leaders within the subject and entry to our distinctive cohort with deep phenotyping throughout a number of domains together with biofluids, excessive subject neuroimaging and behavioural knowledge.The submit is accessible from 01 August 2024, funded by a mix of philanthropic and analysis grant funding for 3 years within the first occasion.In case you want cheap changes or a extra accessible format to use for this job on-line, or have any queries relating to the applying course of, please contact the Institute HR Group (ion.hradmin at ucl.ac.uk).For a full job description and to use for this position please go to UCL’s on-line recruitment portal (https://www.ucl.ac.uk/work-at-ucl/search-ucl-jobs) and search utilizing emptiness reference B02-06685.You will be a registered medical practitioner, permitted to practise within the UK on the graduation of submit, have accomplished common medical coaching to ST2 or equal stage, and possess a really excessive stage of consideration and look after sufferers and analysis topics. Expertise of working in neurology and an curiosity in neurodegenerative illnesses is important, as is demonstrable proficiency in lumbar puncture and the power to work co-operatively in a multidisciplinary setting. Expertise of scientific/translational analysis and of working in Huntington’s illness is fascinating.The position is obtainable within the vary of £43,619 – £67,652 each year together with London Allowance, on the CL, JDPS, or StR scale, depending on NHS contract and/or stage of scientific coaching.In addition to the thrilling alternatives this position presents, we additionally provide some nice advantages; go to https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to seek out out extra.

Anticipated wage

£43619 – 67652 per 12 months

Location

London

Job date

Wed, 20 Mar 2024 05:02:18 GMT

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