Clinical Research Fellow

Job title:

Medical Analysis Fellow

Firm

UCL

Job description

The UCL Huntington’s Illness Centre is uniquely positioned world-wide to translate mechanistic insights to ‘first in human’ research. It combines subtle cell-based programs with rigorously standardised preclinical goal validation to prime mechanistically-driven drug improvement initiatives. The Centre integrates medical and laboratory work with small proof-of-concept first in human research in sufferers within the Leonard Wolfson Experimental Neurology Centre (LWENC) previous to initiating bigger section 2 and three medical trials together with novel huntingtin-lowering trials.We’re recruiting a Medical Analysis Fellow to affix the Centre to work on the Deal with-HD mission, an modern examine funded by Wellcome and led by Professor Sarah J Tabrizi, that seeks to additional perceive neurodegeneration utilizing HD as a mannequin dysfunction. That is an thrilling alternative to affix a world main analysis group who’re main the best way in growing and testing novel therapies for HD sufferers. We now have sturdy partnerships with biotech and pharmaceutical corporations in addition to collaborations with quite a few worldwide educational analysis teams.You’ll primarily drive the medical goals of our HD Younger Grownup Research (HD-YAS): to find out early systems-level pathology and impression on symptomatology in younger grownup HD gene carriers and to determine goal engagement and efficacy markers for future therapeutic trials.This key publish inside Professor Tabrizi’s group will present distinctive analysis and medical expertise in neurogenetics, neurodegenerative illnesses, Huntington’s illness, motion issues, 3T and 7T neuroimaging, CSF biology and biomarkers and cognitive neuroscience.Additionally, you will have the chance to change into concerned within the early section gene remedy and antisense oligonucleotide therapy trials ongoing in HD. You may be an integral a part of the HD Analysis Centre, collaborating within the multidisciplinary HD and neurogenetics clinics on the NHNN, underneath the medical supervision of Professors Sarah Tabrizi and Edward Wild. You’ll have the prospect to review for the next diploma, benefitting from educational help from world leaders within the area and entry to our distinctive cohort with deep phenotyping throughout a number of domains together with biofluids, excessive area neuroimaging and behavioural information.The publish is out there from 01 August 2024, funded by a mix of philanthropic and analysis grant funding for 3 years within the first occasion.For those who want cheap changes or a extra accessible format to use for this job on-line, or have any queries relating to the appliance course of, please contact the Institute HR Group (ion.hradmin at ucl.ac.uk).For a full job description and to use for this function please go to UCL’s on-line recruitment portal ( ) and search utilizing emptiness reference B02-06685.You will be a registered medical practitioner, permitted to practise within the UK on the graduation of publish, have accomplished basic medical coaching to ST2 or equal stage, and possess a really excessive stage of consideration and take care of sufferers and analysis topics. Expertise of working in neurology and an curiosity in neurodegenerative illnesses is important, as is demonstrable proficiency in lumbar puncture and the power to work co-operatively in a multidisciplinary setting. Expertise of medical/translational analysis and of working in Huntington’s illness is fascinating.The function is obtainable within the vary of £43,619 – £67,652 every year together with London Allowance, on the CL, JDPS, or StR scale, depending on NHS contract and/or stage of medical coaching.In addition to the thrilling alternatives this function presents, we additionally provide some nice advantages; go to to seek out out extra.

Anticipated wage

£43619 – 67652 per 12 months

Location

London

Job date

Wed, 20 Mar 2024 03:10:01 GMT

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