Clinical Research Fellow

Job title:

Scientific Analysis Fellow

Firm

College Faculty London

Job description

About usLed by Professor Sarah Tabrizi (Director), Professor Gillian Bates (Co-Director) and Professor Ed Wild (Affiliate Director) and opened in 2015 in a devoted, purpose-built house, the , based mostly within the Division of Neurodegenerative Illness, is uniquely positioned world-wide to translate mechanistic insights to ‘first in human’ research. It combines subtle cell-based methods with rigorously standardised preclinical goal validation to prime mechanistically-driven drug improvement initiatives. The Centre integrates medical and laboratory work with small proof-of-concept first in human research in sufferers within the Leonard Wolfson Experimental Neurology Centre (LWENC) previous to initiating bigger section 2 and three medical trials together with novel huntingtin-lowering trials.In regards to the positionWe are actually recruiting a Scientific Analysis Fellow to hitch the Huntington’s Illness Centre to work on the Deal with-HD venture, an modern research funded by Wellcome and led by Professor Sarah J Tabrizi, that seeks to additional perceive neurodegeneration utilizing HD as a mannequin dysfunction. That is an thrilling alternative to hitch a world main analysis group who’re main the way in which in creating and testing novel therapies for HD sufferers. Now we have sturdy partnerships with biotech and pharmaceutical corporations in addition to collaborations with quite a few worldwide educational analysis teams.You’ll primarily drive the medical goals of our HD Younger Grownup Examine (HD-YAS): to find out early systems-level pathology and influence on symptomatology in younger grownup HD gene carriers and to determine goal engagement and efficacy markers for future therapeutic trials.This key publish inside Professor Tabrizi’s staff will present distinctive analysis and medical expertise in neurogenetics, neurodegenerative ailments, Huntington’s illness, motion issues, 3T and 7T neuroimaging, CSF biology and biomarkers and cognitive neuroscience.Additionally, you will have the chance to change into concerned within the early section gene remedy and antisense oligonucleotide remedy trials ongoing in HD. You’ll be an integral a part of the HD Analysis Centre, collaborating within the multidisciplinary HD and neurogenetics clinics on the NHNN, each beneath the medical supervision of Professors Sarah Tabrizi and Edward Wild. You should have the possibility to review for a better diploma (MD or PhD), benefitting from educational assist from world leaders within the subject and entry to our distinctive cohort with deep phenotyping throughout a number of domains together with biofluids, excessive subject neuroimaging and behavioural knowledge.An honorary contract will likely be sought from UCLH NHS Basis Belief, for which a DBS verify will likely be required.The publish is offered from 01 August 2024 (though there may be flexibility with the beginning date) and is funded by a mix of philanthropic and analysis grant funding for 3 years within the first occasion.For those who want affordable changes or a extra accessible format to use for this job on-line, or have any queries concerning the appliance course of, please contact the Institute of Neurology HR Group ( ).Casual enquiries concerning the position will be addressed to Professor Sarah Tabrizi ( ).A full job description and particular person specification for this position will be accessed beneath.Cut-off date for functions: 23:59, Sunday 21 April 2024.Interview date: Afternoon of Monday, 29 April 2024.About youYou’ll be a registered medical practitioner, permitted to practise within the UK on the graduation of publish, have accomplished basic medical coaching to ST2 or equal stage, and possess a really excessive stage of consideration and take care of sufferers and analysis topics. Expertise of working in neurology and an curiosity in neurodegenerative ailments is important, as is demonstrable proficiency in lumbar puncture and the flexibility to work co-operatively in a multidisciplinary setting. Expertise of medical/translational analysis and of working in Huntington’s illness is fascinating.This position meets the eligibility necessities for a talented employee certificates of sponsorship or a world expertise visa beneath UK Visas and Immigration laws. Due to this fact, UCL welcomes functions from worldwide candidates who require a visa.What we provideThe position is obtainable within the vary of £43,619 – £67,652 every year together with London Allowance, on the CL, JDPS, or StR scale, depending on NHS contract and/or stage of medical coaching.In addition to the thrilling alternatives this position presents, we additionally provide nice advantages, a few of that are beneath:

• 41 Days vacation (27 days annual depart 8 financial institution vacation and 6 closure days)
• Extra 5 days’ annual depart buy scheme
• Outlined profit profession common revalued earnings pension scheme (CARE)
• Cycle to work scheme and season ticket mortgage
• Immigration mortgage
• Relocation scheme for sure posts
• On-site nursery
• On-site health club
• Enhanced maternity, paternity and adoption pay
• Worker help programme: Employees Assist Service
• Discounted medical insurance coverage

Go to to search out out extra.This appointment is topic to UCL Phrases and Situations of Service for Analysis and Skilled Companies Employees. Please go to for extra data.Our dedication to Equality, Range and InclusionThe Institute prides itself on working in an all-inclusive atmosphere irrespective of non-public, bodily, or social traits. Teamwork is extremely valued, particular person strengths are recognised and celebrated, and we’re dedicated to advancing the careers of everybody. 12% of Institute workers are actively engaged on Equality, Range and Inclusion (EDI) initiatives; go to our for extra details about our initiatives and priorities. The Institute additionally holds an , in recognition of our dedication and demonstrable influence in advancing gender equality.As London’s World College, we all know variety fosters creativity and innovation, and we wish our neighborhood to signify the variety of the world’s expertise. We’re dedicated to equality of alternative, to being honest and inclusive, and to being a spot the place all of us belong.We due to this fact notably encourage functions from candidates who’re prone to be underrepresented in UCL’s workforce; these embody folks from Black, Asian and ethnic minority backgrounds, disabled folks, LGBTQI+ and gender numerous folks in all roles, and girls in Grade 9 and 10 roles.Out there paperwork

Anticipated wage

£43619 – 67652 per 12 months

Location

North West London

Job date

Tue, 19 Mar 2024 08:49:57 GMT

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