Vrije Universiteit Brussel
15 Sep 2023
Job Info
- Organisation/Firm
- Vrije Universiteit Brussel
- Division
- Structural Biology Brussels
- Analysis Area
- Organic sciences » Different
Physics » Biophysics
Laptop science » Different - Researcher Profile
- First Stage Researcher (R1)
- Nation
- Belgium
- Software Deadline
- 15 Oct 2023 – 23:59 (Europe/Brussels)
- Kind of Contract
- Non permanent
- Job Standing
- Full-time
- Hours Per Week
- 38
- Supply Beginning Date
- 1 Nov 2023
- Is the job funded by way of the EU Analysis Framework Programme?
- Not funded by an EU programme
- Is the Job associated to workers place inside a Analysis Infrastructure?
- No
Supply Description
As a part of a VUB strategic analysis undertaking for ‘Artificial biology for the event of microbial cell factories’, we’re providing a PhD place the place the (re-)design of regulatory proteins is mixed with modelling their impression on regulation in dynamic organic methods. The place is related to two computational teams on the VUB: i) the Bio2Byte group led by Prof. Dr. Wim Vranken, with concentrate on predicting biophysical protein traits and decoding these predictions in relation to life science issues similar to molecular causes of human ailments or protein design (see https://bio2byte.be/ ) and ii) the group of Prof. Dr. Sophie de Buyl (see https://aphy.analysis.vub.be/prof-dr-sophie-de-buyl ), with curiosity in gaining a elementary understanding of the bodily rules that management the emergent properties of organic methods.
The undertaking will help in designing artificial circuits to manage E. coli metabolism, particularly fatty acid manufacturing pathways. The computational work can be intently linked to experimental validation within the laboratory of Prof. Dr. Eveline Peeters (https://micr.analysis.vub.be/ ), with experience in growing dynamical pathway regulation by way of biosensors. Approaches counting on each transcriptional (DNA) and post-transcriptional (RNA) ranges can be developed and intertwined in iterative computation/experiment cycles. The undertaking depends each on growing approaches in bioinformatics, the place regulatory protein knowledge is collected and analysed in relation to DNA/RNA binding, and in mathematical modelling, the place the mixed impact of introducing such regulatory proteins is studied. The top objective is to create common methods for the environment friendly manufacturing and regulation of metabolites in E. coli.
The three teams have an intensive worldwide community of collaborations inside and out of doors of Europe. We provide an open, dynamic and rewarding analysis surroundings, targeted on teamwork and collaborations, that stimulates initiative taking, dialogue and originality.
Necessities
- Analysis Area
- All
- Training Degree
- Grasp Diploma or equal
Expertise/{Qualifications}
Candidates should maintain a grasp’s diploma in physics, arithmetic, chemistry, (bio)engineering or equal. Expertise with organic and/or dynamical modelling is a bonus. Candidates should be proficient in each written and oral English. Private and relational qualities can be emphasised.
- Languages
- ENGLISH
- Degree
- Good
Extra Info
Advantages
https://jobs.vub.be/content material/Advantages/?locale=en_GB
Extra feedback
The place is instantly obtainable and funded for the total period of the PhD. You may be primarily positioned on the (IB)2 Interuniversity Institute of Bioinformatics in Brussels (http://ibsquare.be/ ), Etterbeek VUB/ULB campus, which offers an interdisciplinary surroundings throughout sciences and (bio-)engineering.
Please contact [email protected] and [email protected] for extra info. To use, please fill in and submit this on-line type: https://bit.ly/phd_compsynbio . You need to embrace 1) a motivation letter detailing your curiosity and suitability for this place and a couple of) a duplicate of your Grasp’s diploma and three) a CV together with at the very least 1 contact for reference. Extra info could be uploaded through the appliance type. The place is open till stuffed.
Work Location(s)
- Variety of presents obtainable
- 1
- Firm/Institute
- Vrije Universiteit Brussel
- Nation
- Belgium
- State/Province
- Brussels
- Metropolis
- Brussels
- Postal Code
- 1050
- Road
- Pleinlaan 2
- Geofield
The place to use
- Web site
- https://bit.ly/phd_compsynbio
Contact
- Metropolis
- Brussels
- Web site
- http://we.vub.ac.be/en/structural-biology-brussels
- Road
- Pleinlaan 2
- Postal Code
- 1050
STATUS: EXPIRED
View or Apply
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