Internal – Research Associate in Bioinformatics and Machine Learning
Cardiff University
School / DirectorateSchool of MedicineAdvertThis post is currently open to employees of Cardiff University only. Please do not apply if you do not have a current contract of employment with the University.Internal Applicants Only – Research Associate in Bioinformatics and Machine Learning
Division of Psychological Medicine and Clinical Neurosciences
School of Medicine
College of Biomedical and Life SciencesWe have an exciting opportunity to appoint an enthusiastic and experienced Bioinformatician to join Professor Valentina Escott-Price’s research group within the UK Dementia Research Institute at Cardiff University. The post holder will play a leading role in the analysis of large and complex genetic datasets with a range of Machine Learning approaches, whilst leading a broad range of investigative and analytical activities to maximally exploit gene x gene and gene x environment interactions in clinical and genetic data and linking them to an individual risk score with the aim to reveal novel therapeutic targets in dementia. They will help refine inclusion criteria for future clinical trials and ultimately translate into guidance for personalized healthcare decisions. The successful applicant will have the opportunity to take part in cutting-edge research investigating the complex architecture of dementia and related subphenotypes in human data.In this role, you will work independently and as part of a multi-disciplinary team, to perform self-directed analyses using in house and publicly available datasets for high impact, peer-reviewed publications. Applicants should be knowledgeable and enthusiastic with the ability to multi-task and communicate effectively. Core tasks will include data analysis and management of genetic, genomic and related phenotypic data from dementia case-control and cohort samples, publicly available and in-house generated genomic human data. Collaborative working is a key component of this role meaning that communication skills will be vital, in order to cultivate international collaborations from a number of academic institutions.We’d like to hear from you if you have a background in machine learning and biostatistics with proven experience of extensive large-scale data analyses and manipulation, including analysis of genome-wide association studies and genetic interactions. Expert knowledge of data manipulation in a UNIX/Linux environment and proficiency in high level programming languages such as Python and R Statistics is essential. Knowledge of techniques used in genetics and epidemiology, as well as experience in using software used for the analysis of genomic data such as PLINK, LDScore, is desirable.For informal enquiries please contact Professor Valentina Escott-Price ( )This post is full-time (35 hours per week), available from 01.11.2024 and fixed term until 30.09.2025, based at the Hadyn Ellis Building, Cathays campus.Salary: £40,247 – £45,163 per annum (Grade 6). Appointments to roles at Cardiff University are usually made at bottom of scale unless in exceptional circumstances.The majority of roles at Cardiff University are currently operating under “blended working” arrangements, with staff having the flexibility to work partly from home and partly from the University campus depending on specific business requirements. Discussions around these arrangements can take place after the successful candidate has been appointed.Cardiff University offers many excellent benefits, including 45 days annual leave (incl bank holidays), local pension scheme, a cycle to work scheme and other travel initiatives, annual increments within the pay scale, and more. It is an exciting and vibrant place to work, with many different challenges and is a proud Living Wage supporter.Closing date: 11 November 2024External applications are currently not being considered for this post. If the decision is made to open the post to external candidates, the strapline at the top will be removed and you will be given ample time to apply – please check back periodically for details.Cardiff University is committed to supporting and promoting equality and diversity and to creating an inclusive working environment. We believe this can be achieved through attracting, developing, and retaining a diverse range of staff from many different backgrounds. We therefore welcome applicants from all sections of the community regardless of sex, ethnicity, disability, sexual orientation, trans identity, relationship status, religion or belief, caring responsibilities, or age. In supporting our employees to achieve a balance between their work and their personal lives, we will also consider proposals for flexible working or job share arrangements.Cardiff University is a signatory to the San Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions we will evaluate applicants on the quality of their research, not publication metrics or the identity of the journal in which the research is published. More information is available at:Applications may be submitted in Welsh, and an application submitted in Welsh will not be treated less favourably than an application submitted in English.Post Reference Number19246BRJob DescriptionJob Purpose
To conduct research principally within biostatistics, Machine Learning and bioinformatics associated with Alzheimer’s disease and dementia genetics in larger population studies, and to contribute to the overall research performance of the School and University, carrying out research leading to the publishing of work in high-quality journals. To pursue excellence in research and to inspire others to do the same.Duties and ResponsibilitiesKey DutiesResearch
Other
Salary Range Max.45,163GradeGrade 6Salary Range Min.40,247Job CategoryAcademic – Research, Health, Medical & DentalAdditional InformationIMPORTANT: Evidencing Criteria
Candidates should evidence that they meet ALL of the essential criteria as well as, where relevant, the desirable criteria.As part of the application process, you will be asked to provide this evidence via a supporting statement. Please ensure when submitting this document / attaching it to you application profile you name it with the vacancy reference number, in this instance, 19246BRThe project is embedded within the UK Dementia Research Institute at Cardiff University. The post holder will work with Prof. Valentina Escott Price, and will attend and contribute to meetings and seminars. There will be an opportunity to interface with a variety of international cohorts for data analysis, and the opportunity to publish in high quality journalsHow we will support you in performing in this role
There are some things that you must have before you can start this role (see ‘Essential Criteria’), but other things can be developed either through training, or just by general on-the-job experience. We want to support and develop you once you have started in the role using a combination of the following to get the best out of you:1. Regular one-to-ones with your manager
2. An experienced and supportive team around you
3. Supporting you through job-relevant training and development that you may require
4. A mentoring schemeCareer PathwayResearchPerson SpecificationEssential CriteriaQualifications and Education * Postgraduate degree at PhD level (or nearing completion / submission) in a related subject area or relevant industrial experience.
Knowledge, Skills and Experience * An established expertise and proven portfolio of research and/or relevant industrial experience within the following research fields:– Biostatistics/Bioinformatics in complex genetic analyses
– Genetics of complex diseases
– High Performance Computing
– Big data manipulation and analyses
– Machine Learning * Knowledge of current status of research in biostatistics, bioinformatics, machine learning, data simulation techniques, genetic interaction analyses.
Communication and Team Working * Proven ability in effective and persuasive communication.
Other * Proven ability to demonstrate creativity, innovation and team-working within work
Desirable Criteria * Undergraduate background/modules in either/or Psychology, Neuroscience, Computer Science or Mathematics.
£40247 – 45163 per year
United Kingdom
Wed, 06 Nov 2024 07:51:52 GMT
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