Medicine Swansea University Research Excellence Scholarships (SURES): Fully Funded PhD Scholarship: Hormone-Immune Signalling in Parkinson’s Dementia

Job title:

Drugs Swansea College Analysis Excellence Scholarships (SURES): Totally Funded PhD Scholarship: Hormone-Immune Signalling in Parkinson’s Dementia

Firm

Swansea College

Job description

Job Info Organisation/FirmSwansea College DivisionCentral Analysis AreaMedical sciences » Drugs Researcher ProfileFirst Stage Researcher (R1) NationUnited Kingdom Software Deadline3 Apr 2024 – 23:59 (Europe/London) Sort of ContractDifferent Job StandingFull-time Hours Per Week35 Provide Beginning Date1 Oct 2024 Is the job funded via the EU Analysis Framework Programme?Not funded by an EU programme Is the Job associated to employees place inside a Analysis Infrastructure?NoProvide DescriptionDrugs: Swansea College Analysis Excellence Scholarships (SURES): Totally Funded PhD Scholarship: Hormone-Immune Signalling in Parkinson’s DementiaSwansea College is happy to supply fully-funded Swansea College Analysis Excellence Scholarships (SURES) for full-time doctoral college students to its fifth cohort, commencing in October 2024.Parkinson’s illness (PD) is the second most prevalent neurodegenerative illness, effecting 10 million individuals worldwide. PD is characterised by motor and non-motor impairments – with
70% progressing to dementia at an accelerated price. Present remedies for the motor impairments work in ~50% of these affected and don’t deal with the underlying pathology, whereas there isn’t any efficient remedy for dementia. A remedy that slows dementia development would have unprecedented affect on the well being and social care sectors.The first goal of this venture is to develop a drug that stops dangerous mind irritation and helps mind plasticity to deal with PD dementia.This analysis builds on Dr Davies’ lab findings at Swansea College Medical Faculty (SUMS) that utilized in silico instruments, in collaboration with Dr Mullins (SUMS), to determine novel small-molecule compounds that modulate ghrelin bioavailability. The scholar will decide whether or not enzyme focusing on small molecules modify acyl-ghrelin signalling each in neuronal cell tradition programs and human T-lymphocytes related to PD dementia.This venture, supported by MRC Growth Pathway Hole Funding and in collaboration with the Alzheimer’s Analysis UK Drug Discovery Institute (ARUK DDI) at College School London (UCL), will speed up the event of latest compounds. The SURES pupil will be a part of Dr Davies’ lab, working as a part of a multi-disciplinary workforce encompassing nerve cell perform (Dr Davies), irritation (Dr Jones, SUMS), in silico drug design (Dr Mullins) and medicinal chemistry experience (Professor Ducotterd, ARUK DDI, UCL), to develop new remedies for PD dementia the place there may be vital un-met want.The scholar may even work alongside colleagues to develop a companion diagnostic mass-spectrometry-based blood take a look at to facilitate drug efficacy monitoring. The SURES pupil will decide whether or not our not too long ago developed Bead Assisted Mass Spectrometry (BAMS) take a look at, working in collaboration with Dr Angelini (SUMS), represents an correct diagnostic instrument to observe ghrelin bioavailability.This venture is aligned with two of the newly established School of Drugs, Well being and Life Science Analysis Institutes, particularly, Wholesome Ageing & Persistent Circumstances and Superior Diagnostic and Medical Applied sciences. The SURES pupil will work carefully with collaborative groups and with FMHLS Institutes to maximise the affect of our analysis to the College and to the broader society.NecessitiesAnalysis Area Medical sciences » Drugs Training Degree Bachelor Diploma or equalExpertise/{Qualifications}Candidates will need to have attained, or should be anticipated to realize, a first-class honours diploma and/or a distinction at grasp’s degree. If you’re eligible to use for the scholarship (i.e. a pupil who’s eligible to pay the UK price of tuition charges) however don’t maintain a UK diploma, you’ll be able to examine our comparability entry necessities. Please be aware that you could be want to offer proof of your English Language proficiency.Particular Necessities

• The place candidates have a number of grasp’s levels, a distinction should be held within the diploma that’s most related to the supposed PhD examine.
• If you’re at the moment finding out for a grasp’s degree qualification with an anticipated award date that’s later than 01/10/2024, it is best to maintain a minimal of an upper-second-class (2:1) honours diploma.
• It is best to be capable of exhibit a go with a minimal grade common of no less than 70% to your part-one grasp’s diploma modules (the taught side of your grasp’s course slightly than a research-focused dissertation) and submit your dissertation by no later than 30/09/2024.

Candidates should be capable of start their course of examine in October 2024. As a cohort-based programme, deferral to an alternate enrolment window inside the educational yr or to a different educational yr just isn’t permissible.Please be aware that each the diploma and language-proficiency entry necessities for SURES are greater than the baseline normal for entry that’s stipulated for many of the PhD programmes at Swansea College.As a consequence of funding restrictions, this scholarship is open to candidates eligible to pay tuition charges on the UK price solely, as outlined by .Further InfoAdvantagesThis scholarship covers the total value of UK tuition charges and an annual stipend at £19,237.Further analysis bills may even be accessible.Eligibility standardsCandidates will need to have attained, or should be anticipated to realize, a first-class honours diploma and/or a distinction at grasp’s degree. If you’re eligible to use for the scholarship (i.e. a pupil who’s eligible to pay the UK price of tuition charges) however don’t maintain a UK diploma, you’ll be able to examine our comparability entry necessities. Please be aware that you could be want to offer proof of your English Language proficiency.

• The place candidates have a number of grasp’s levels, a distinction should be held within the diploma that’s most related to the supposed PhD examine.
• If you’re at the moment finding out for a grasp’s degree qualification with an anticipated award date that’s later than 01/10/2024, it is best to maintain a minimal of an upper-second-class (2:1) honours diploma.
• It is best to be capable of exhibit a go with a minimal grade common of no less than 70% to your part-one grasp’s diploma modules (the taught side of your grasp’s course slightly than a research-focused dissertation) and submit your dissertation by no later than 30/09/2024.

Candidates should be capable of start their course of examine in October 2024. As a cohort-based programme, deferral to an alternate enrolment window inside the educational yr or to a different educational yr just isn’t permissible.Please be aware that each the diploma and language-proficiency entry necessities for SURES are greater than the baseline normal for entry that’s stipulated for many of the PhD programmes at Swansea College.As a consequence of funding restrictions, this scholarship is open to candidates eligible to pay tuition charges on the UK price solely, as outlined by .Choice course ofPlease see our web site for extra info.Web site for extra job particularsWork Location(s)Variety of provides accessible 1 Firm/Institute Swansea College Nation United Kingdom Metropolis Swansea Postal Code SA2 8PP GeofieldThe place to use Web siteContact MetropolisSwansea Web siteAvenueSingleton Park Postal CodeSA28PP E-MailJeff.s.davies@swansea.ac.ukSTATUS: EXPIRED

Anticipated wage

£19237 per yr

Location

Swansea

Job date

Thu, 14 Mar 2024 02:43:16 GMT

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