Medicine Swansea University Research Excellence Scholarships (SURES): Fully Funded PhD: The In Vivo Mechanistic Dissection of Lifespan Extension Pathways

Job title:

Medication Swansea College Analysis Excellence Scholarships (SURES): Totally Funded PhD: The In Vivo Mechanistic Dissection of Lifespan Extension Pathways

Firm

Swansea College

Job description

Job Data Organisation/FirmSwansea College DivisionCentral Analysis DisciplineMedical sciences » Medication Researcher ProfileFirst Stage Researcher (R1) NationUnited Kingdom Utility Deadline10 Apr 2024 – 23:59 (Europe/London) Sort of ContractDifferent Job StandingFull-time Hours Per Week35 Provide Beginning Date1 Oct 2024 Is the job funded by way of the EU Analysis Framework Programme?Not funded by an EU programme Is the Job associated to employees place inside a Analysis Infrastructure?NoProvide DescriptionMedication: Swansea College Analysis Excellence Scholarships (SURES): Totally Funded PhD: The In Vivo Mechanistic Dissection of Lifespan Extension PathwaysSwansea College is happy to supply fully-funded Swansea College Analysis Excellence Scholarships (SURES) for full-time doctoral college students to its fifth cohort, commencing in October 2024.Ageing is a rising basic financial and social problem because the age construction of our inhabitants will change markedly throughout this century. Regardless of important enhancements in residing situations and healthcare resulting in rising life expectancy, this can be very uncommon to develop outdated in good well being and by the age of 85 primarily no particular person is disease-free. As such, drug discovery analysis is specializing in potential interventions that improve the human well being span. One space of analysis focus is on the reversal of mobile senescence, and so there was a fast improvement of interventions that behave as senolytic medicine. One such drug is Resveratrol, a naturally occurring plant compound that’s thought to reverse mobile senescence by way of its motion on SIRT1.The particular intention of the undertaking is to make use of Resveratrol, and associated senolytic compounds, to establish ageing pathways in a brand new in vivo mannequin of ageing the African Turquoise Killifish (Nothobranchius furzeri). The undertaking will examine the impact of mid-lifespan dosing of Resveratrol and comparable compounds on lifespan and ageing (senescence) markers in Killifish utilizing RNA-seq and proteomic approaches. As soon as novel pathways are recognized, the undertaking will then use gene modifying (CRISPR/Cas9) of Killifish to validate these novel mechanisms of senescence reversal.This undertaking will likely be a collaboration between the Murray laboratory at Swansea College, and the Faragher laboratory, on the College of Brighton.NecessitiesAnalysis Discipline Medical sciences » Medication Schooling Stage Bachelor Diploma or equalExpertise/{Qualifications}Candidates will need to have attained, or should be anticipated to achieve, a first-class honours diploma and/or a distinction at grasp’s stage. If you’re eligible to use for the scholarship (i.e. a pupil who’s eligible to pay the UK price of tuition charges) however don’t maintain a UK diploma, you’ll be able to verify our comparability entry necessities. Please observe that you could be want to offer proof of your English Language proficiency.Particular Necessities

• The place candidates have a number of grasp’s levels, a distinction should be held within the diploma that’s most related to the meant PhD examine.
• If you’re presently learning for a grasp’s stage qualification with an anticipated award date that’s later than 01/10/2024, it is best to maintain a minimal of an upper-second-class (2:1) honours diploma.
• You must be capable to show a cross with a minimal grade common of at the least 70% in your part-one grasp’s diploma modules (the taught facet of your grasp’s course quite than a research-focused dissertation) and submit your dissertation by no later than 30/09/2024.

Candidates should be capable to start their course of examine in October 2024. As a cohort-based programme, deferral to another enrolment window inside the educational yr or to a different educational yr will not be permissible.Please observe that each the diploma and language-proficiency entry necessities for SURES are larger than the baseline normal for entry that’s stipulated for many of the PhD programmes at Swansea College.Resulting from funding restrictions, this scholarship is open to candidates eligible to pay tuition charges on the UK price solely, as outlined by .Further DataAdvantagesThis scholarship covers the complete price of UK tuition charges and an annual stipend at £19,237.Further analysis bills can even be accessible.Eligibility standardsCandidates will need to have attained, or should be anticipated to achieve, a first-class honours diploma and/or a distinction at grasp’s stage. If you’re eligible to use for the scholarship (i.e. a pupil who’s eligible to pay the UK price of tuition charges) however don’t maintain a UK diploma, you’ll be able to verify our comparability entry necessities. Please observe that you could be want to offer proof of your English Language proficiency.

• The place candidates have a number of grasp’s levels, a distinction should be held within the diploma that’s most related to the meant PhD examine.
• If you’re presently learning for a grasp’s stage qualification with an anticipated award date that’s later than 01/10/2024, it is best to maintain a minimal of an upper-second-class (2:1) honours diploma.
• You must be capable to show a cross with a minimal grade common of at the least 70% in your part-one grasp’s diploma modules (the taught facet of your grasp’s course quite than a research-focused dissertation) and submit your dissertation by no later than 30/09/2024.

Candidates should be capable to start their course of examine in October 2024. As a cohort-based programme, deferral to another enrolment window inside the educational yr or to a different educational yr will not be permissible.Please observe that each the diploma and language-proficiency entry necessities for SURES are larger than the baseline normal for entry that’s stipulated for many of the PhD programmes at Swansea College.Resulting from funding restrictions, this scholarship is open to candidates eligible to pay tuition charges on the UK price solely, as outlined by .Choice course ofPlease see our web site for extra data.Web site for extra job particularsWork Location(s)Variety of gives accessible 1 Firm/Institute Swansea College Nation United Kingdom Metropolis Swansea Postal Code SA2 8PP GeofieldThe place to use Web siteContact MetropolisSwansea Web siteAvenueSingleton Park Postal CodeSA28PP E-Mailj.t.murray@swansea.ac.ukSTATUS: EXPIRED

Anticipated wage

£19237 per yr

Location

Swansea

Job date

Thu, 14 Mar 2024 05:13:58 GMT

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