University College London
About the Project
The UCL Division of Medicine is offering a fully funded 36 months PhD studentship within UCL Respiratory Research Department to a highly motivated candidate.
The studentship is expected to start 1st September 2024, although this date is flexible.
The PhD student will work on a Rosetrees Trust funded interdisciplinary project working closely between Professor Jeremy Brown’s research group, UCL Respiratory, Division of Medicine, UCL (https://profiles.ucl.ac.uk/5245-jeremy-brown/about) and Professor Bart Hoogenboom’s research group, London Centre for Nanotechnology (https://profiles.ucl.ac.uk/9851-bart-hoogenboom).
About the role
The PhD Student will be based at the Rayne building, 5 University Street.
The main purpose of this project is to work on the development of a novel therapy for antibiotic resistant Acinetobacter baumannii infections. The student will work closely with an MRC-funded team developing a monoclonal antibody treatment for A. baumannii. They will assess the efficacy of antibody to selected protein antigen targets at promoting bacterial killing using a combination of immunological assays and advanced microscopic techniques to measure at the molecular level formation of the Membrane Attack Complex on A. baumannii. By combining Brown’s expertise in bacterial biology and immunology with the techniques available in the Hoogenboom laboratory this project will provide nanoscale characterisation of immune interactions on the A. baumannii bacterial outer membrane and obtain highly novel data on the functional consequences of antibody binding to different A. baumannii outer membrane target antigens.
For more details, a job description and person specification can be accessed at the bottom of this page.
General enquiries regarding the post can be made to Professor Jeremy Brown ([email protected]).
How to Apply:
Please do not click the ‘Apply Now’ button next to the advert.
To apply, please send a current CV including the contact details of two professional referees as well as a 1-sided A4 cover letter to Professor Jeremy Brown at [email protected].
Closing deadline for applications: 30th June 2024 at 23:59.
Interview date to be confirmed.
Applications that are submitted without following the correct application process will not be considered.
About you
The studentship is suitable for someone who has recently completed a BSc degree in a discipline related to immunology or microbiology, with research experience in a discipline relevant for immunology, molecular biology, microbiology, microscopy or vaccinology. A Master’s qualification in a related discipline would be advantageous. Also, specific prior experience in analysing immunological responses to infection would be desirable.
What we offer
The studentship provides an annual stipend of £21,237 initially increasing to £22,523 by the third year and covers UK Home fees which are available for UK citizens or those who have settled status in the UK. You can contact the UCL Graduate Admissions Office for advice should you be unsure whether or not you meet the eligibility criteria for Home fee status. Further information on Brexit and the definitions for fee status assessment can be found on the UCL Student fee status page and also the UKCISA website (Higher Education: Definitions for fee status assessment).
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