University of Southampton
Supervisory Group: Professor Gill Reid & Dr Richard Knoghton
Venture Description:
Growing new chelate scaffolds for binding radiofluorine and radiometals – in the direction of mixed theragnostic brokers for imaging and remedy in drugs
Purposes are invited from suitably certified and motivated candidates for an EPSRC CASE PhD studentship based mostly in Chemistry on the College of Southampton, in collaboration with companions at GE Healthcare. The challenge focusses on growth of latest steel complexes for radiofluorination for potential functions as subsequent technology medical imaging brokers by way of positron emission tomography (PET) – an necessary and extensively used medical imaging method utilized in hospitals and clinics for detection of illnesses equivalent to cancers.
This challenge is on the coordination chemistry/radiochemistry interface and the profitable applicant can have the chance to develop expertise within the synthesis and characterisation of steel fluoride complexes with macrocyclic co-ligands as doable PET tracer candidates, in addition to to make use of GE Healthcare’s services at St Thomas’ Hospital (London) to develop environment friendly strategies for his or her radiofluorination (with the fluorine-18 isotope), purification and stability testing. The potential of the compounds for incorporating radiometals may also be explored.
The profitable candidate will be a part of a well-established analysis exercise in Chemistry at Southampton and can have entry to state-of-the artwork services for the synthesis and characterisation of inorganic coordination complexes. Candidates ought to maintain or be about to carry a 1st class or 2:1 diploma in Chemistry or a intently associated topic and have a eager curiosity in each the artificial and radiochemical facets of the challenge. Analysis expertise in molecular inorganic chemistry/coordination chemistry and inert ambiance strategies can be advantageous.
Full funding for this challenge is accessible for 42 months, sponsored by EPSRC and GE Healthcare. Please observe that resulting from funding restrictions this place is open to UK candidates solely. The coed might be supervised by Professor Gill Reid and Dr Richard Knighton.
In case you want to focus on any particulars of the challenge informally, please contact Professor Gill Reid, Electronic mail: [email protected]
Entry Necessities
An excellent undergraduate diploma (not less than a UK 2:1 honours diploma, or its worldwide equal).
Closing Date : 31 August 2024. Purposes might be thought of within the order that they’re obtained, the place might be thought of stuffed when an appropriate candidate has been recognized.
Funding: We provide a variety of funding alternatives together with Bursaries and Scholarships. For extra info please go to PhD Scholarships Doctoral School College of Southampton . Funding might be awarded on a rolling foundation, so apply early for the perfect alternative to be thought of.
How To Apply
Apply on-line: HERE Choose programme sort (Analysis), 2024/25, College of Engineering and Bodily Sciences, subsequent web page choose “PhD Chemistry (Full time)”. In Part 2 of the applying type it is best to insert the title of the supervisor Prof Gill Reid.
Purposes ought to embrace:
Analysis Proposal
Curriculum Vitae
Two reference letters
Diploma Transcripts/Certificates to this point
For additional info please contact: [email protected]
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