University of Oxford
Job title:
Submit-doctoral Analysis Assistant neuronal biologist: “Biomarkers of lysosomal dysfunction in Parkinson’s illness”
Firm
College of Oxford
Job description
Submit-doctoral Analysis Assistant neuronal biologist: “Biomarkers of lysosomal dysfunction in Parkinson’s illness”
Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Constructing, South Parks Highway, Oxford, OX1 3PTFull-time, Fastened-term for two yearsPurposes are invited for a post-doctoral neuronal biologist to work on biomarker profiles of lysosomal dysfunction in pre-clinical fashions of Parkinson’s. The undertaking, funded by the Michael J Fox Basis and in collaboration with EndLyz, a brand new firm throughout the Dementia Discovery Fund (DDF) portfolio, represents an thrilling alternative to undertake translational work on the interface between tutorial analysis and pharmaceutical goal and drug discovery in an distinctive setting. The undertaking will study metabolomic biomarkers of endolysosomal dysfunction to raised perceive mechanisms of illness pathology, and to determine how the biomarker profile might change on therapy with potential therapeutic compounds.Duties embrace design and implementation of experiments; interpretation of information; metabolomic profiling in Parkinson’s transgenic mouse fashions; biochemistry, immunohistochemistry and molecular neuropathology research in mind samples from transgenic mice; preparation of information for publication; contribute concepts for brand spanking new analysis initiatives and develop concepts for producing analysis earnings; handle personal tutorial analysis involving small-scale undertaking administration and act as a supply of data to different members of the group.You should have glorious information and sensible expertise of working with pre-clinical transgenic fashions of neurodegenerative illness. The flexibility to innovate, trouble-shoot technical issues, be meticulous in sensible work and in file conserving can also be important. Candidates should maintain, or be close to completion of, a PhD/DPhil in a related space of analysis and have expertise in mobile neuroscience, and molecular cell biology related to evaluation of neuronal phenotypes.The publish is obtainable for 2 years from 1st January 2024. The publish might be primarily based within the Laboratory of Molecular Neurodegeneration, Kavli Institute for Nanoscience Discovery, South Parks Highway, Oxford, OX1 3PT.Casual enquiries could also be directed Professor Richard Wade-Martins ([email protected]).Deadline for functions is noon on Thursday 11 April 2024.Interviews are prone to be held on the week starting 22 April 2024.Purposes are notably welcome from girls, black and minority ethnic candidates who’re under-represented in tutorial posts in Oxford.Whereas this can be a full-time function, we welcome functions from people who want to be thought-about for part-time working or different versatile working preparations.We, as a Division and Neighborhood, might be thoughtful and welcoming of all individuals, no matter race, ethnicity, faith, incapacity, sexual orientation and gender id. We acknowledge societal inequalities and the way these influence us, and people round us, personally and professionally. – DPAG Assertion of Inclusion
Contact Particular person : HR Staff Emptiness ID : 169118
Contact Cellphone : 01865 282167 Closing Date & Time : 11-Apr-2024 12:00
Pay Scale : STANDARD GRADE 7 Contact E-mail :
Wage (£) : 36024 – 44263
Anticipated wage
Location
Oxford
Job date
Fri, 15 Mar 2024 03:26:00 GMT
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