Smith College
NORTHAMPTON Postdoctoral Fellow JOB SUMMARY The Division of Chemistry
at Smith School invitations purposes for a 2-year, full-time,
benefits-eligible Postdoctoral Fellow inside the laboratory of Dr.
Lesley-Ann Giddings. The Giddings lab research microbial secondary
metabolism in excessive environments and seeks a Postdoctoral Fellow to
conduct analysis on the kinetic characterization and evolution of
enzymes concerned in siderophore biosynthesis. This venture is funded by
the Nationwide Science Basis grant, CAREER: Characterization and
Evolution of N-hydroxylase Biocatalysts: Options to Catalysis and
Remediating Steel Air pollution. A Ph.D. in Chemistry, Biology or associated
areas is predicted by the point of appointment and the specified begin date
is Spring 2024. Girls, traditionally underrepresented minorities,
veterans, and people with disabilities are inspired to use. The
objective of the venture is to make use of a yeast-based exercise display to straight
evolve siderophore biosynthetic enzymes to just accept unnatural substrates
in addition to characterize new enzymes from metal-polluted environments.
Particular experimental targets embody growing and utilizing a excessive
throughput yeast-based display for directed evolution, getting ready mutant
and DNA libraries, performing metagenomic sequencing, protein expression
and purification, and enzyme kinetics. Related publications embody
PLOS ONE, PMID: 33784308 and PMID: 32785287. Different tasks
embody co-writing peer-reviewed articles, mentoring undergraduate
researchers within the laboratory, and taking part in weekly lab conferences.
Participation in undergraduate programs is feasible though not
required. Candidates will even be supplied monetary assist for
conferences/workshop journey and profession growth. MINIMUM
QUALIFICATIONS Ph.D. in chemistry, biology, chemical or biomedical
engineering, or a associated self-discipline. PREFERRED QUALIFICATIONS A super
candidate can have experience performing protein engineering in yeast,
metagenomic sequencing, and bioinformatic analyses. SKILLS Mutagenesis,
protein expression and purification, enzyme kinetics, and the power to
write scientific manuscripts in a well timed method. ADDITIONAL INFORMATION
Please contact Lesley-Ann Giddings ([email protected]) with any
questions.
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