Postdoctoral Research Assistant

Concerning the Function

Purposes are invited for a full-time Postdoctoral Analysis Assistant to analyze mechanical sensing in cardiac muscle cells and its involvement in heart problems.

Cardiovascular ailments are the key reason behind mortality worldwide, but there may be nonetheless a scarcity of efficient therapies. Latest analysis more and more emphasised that modifications to mechanical sensing and signalling critically influences the illness onset and progression1-5. Our current information indicated a novel mechanosensitive complicated on the cell-cell contacts of cardiomyocytes, the contractile cells within the coronary heart, which we need to examine right here in additional element, utilizing main cardiomyocyte cultures, bioengineering and superior microscopy instruments.

The place might be based mostly on the Iskratsch lab . The mission is a collaboration with Prof Andrew Tinker to analyze the implications on the cardiomyocyte electrophysiology and Prof Cesare Terracciano to review this complicated at tissue degree utilizing myocardial slice cultures6, for which the candidate may also carry out work at Imperial School London.

Our analysis teams prioritize a wholesome analysis tradition, collaboration, and versatile work hours as wanted. We’ll present personalised mentorship to the profitable candidate. Earlier group members continued to careers in academia and business.

Iskratsch et al., Nat Rev Cell Mol Biol (2013)

(2018)

Marhuenda et al, BioRxiv (2023)

Swiatlowska et al, Sci Adv (2022)

Swiatlowska et al, Adv Sci (2024)

Pitoulis et al, Cardiovasc Res (2022)

About You

The profitable candidate might be a extremely motivated, interdisciplinary group employee with experience in bioengineering, or mechanobiology and powerful again floor in cell and ideally cardiovascular biology.

Concerning the Faculty/Division/Institute/Challenge

This submit is inside the Faculty of Engineering and Supplies Science (SEMS), the place the profitable candidate can have entry to a wide range of apparatus together with state-of-the artwork microscopes, bio- and nanofabrication tools, mechanical and structural characterisation and tools for mechanical stimulation.

About Queen Mary

At Queen Mary College of London, we imagine {that a} range of concepts helps us obtain the beforehand unthinkable.

All through our historical past, we’ve fostered social justice and improved lives by means of tutorial excellence. And we proceed to reside and breathe this spirit at present, not as a result of it’s merely ‘the appropriate factor to do’ however for what it helps us obtain and the mental brilliance it delivers.

Our reformer heritage informs our conviction that nice concepts can and may come from anyplace. It’s an strategy that has introduced outcomes throughout the globe, from the communities of east London to the favelas of Rio de Janeiro.

We proceed to embrace range of thought and opinion in every little thing we do, within the perception that when views collide, disciplines work together, and views intersect, really unique thought takes type.

Advantages

In return, we provide 30 days’ go away every year, entry to a pension scheme, a season ticket mortgage scheme and aggressive salaries. We additionally provide enhanced household pleasant go away, and an on-site nursery on the Mile Finish campus. Additionally, you will work with a pleasant group, with private growth alternatives.

Queen Mary’s dedication to our various and inclusive neighborhood is embedded in our appointments processes. Affordable changes might be made at every stage of the recruitment course of for any candidate with a incapacity.