Postdoctoral Research Assistant

Division: Faculty of Engineering & Supplies Science
Wage: £40,223 – £47,178 each year (Grade 4)
Reference: 1718
Location: Mile Finish
Date posted: 18 March 2024
Deadline: 13 Could 2024

Additional particulars and apply

Overview

In regards to the Function

Functions are invited for a full-time Postdoctoral Analysis Assistant to analyze mechanical sensing in cardiac muscle cells and its involvement in heart problems.

Cardiovascular illnesses are the most important explanation for mortality worldwide, but there’s nonetheless a scarcity of efficient therapies. Current analysis more and more emphasised that adjustments to mechanical sensing and signalling critically influences the illness onset and progression1-5. Our current knowledge indicated a novel mechanosensitive complicated on the cell-cell contacts of cardiomyocytes, the contractile cells within the coronary heart, which we need to research right here in additional element, utilizing major cardiomyocyte cultures, bioengineering and superior microscopy instruments.

The place can be based mostly on the Iskratsch lab . The venture is a collaboration with Prof Andrew Tinker to analyze the implications on the cardiomyocyte electrophysiology and Prof Cesare Terracciano to review this complicated at tissue degree utilizing myocardial slice cultures6, for which the candidate will even carry out work at Imperial School London.

Our analysis teams prioritize a wholesome analysis tradition, collaboration, and versatile work hours as wanted. We’ll present personalised mentorship to the profitable candidate. Earlier group members continued to careers in academia and business.

Iskratsch et al., Nat Rev Cell Mol Biol (2013)

(2018)

Marhuenda et al, BioRxiv (2023)

Swiatlowska et al, Sci Adv (2022)

Swiatlowska et al, Adv Sci (2024)

Pitoulis et al, Cardiovasc Res (2022)

About You

The profitable candidate can be a extremely motivated, interdisciplinary workforce employee with experience in bioengineering, or mechanobiology and powerful again floor in cell and ideally cardiovascular biology.

In regards to the Faculty/Division/Institute/Undertaking

This publish is throughout the Faculty of Engineering and Supplies Science (SEMS), the place the profitable candidate can have entry to a wide variety of apparatus together with state-of-the artwork microscopes, bio- and nanofabrication tools, mechanical and structural characterisation and tools for mechanical stimulation.

About Queen Mary
At Queen Mary College of London, we imagine {that a} range of concepts helps us obtain the beforehand unthinkable.

All through our historical past, we’ve fostered social justice and improved lives by tutorial excellence. And we proceed to reside and breathe this spirit at present, not as a result of it’s merely ‘the best factor to do’ however for what it helps us obtain and the mental brilliance it delivers.

Our reformer heritage informs our conviction that nice concepts can and may come from anyplace. It’s an strategy that has introduced outcomes throughout the globe, from the communities of east London to the favelas of Rio de Janeiro.

We proceed to embrace range of thought and opinion in the whole lot we do, within the perception that when views collide, disciplines work together, and views intersect, really unique thought takes kind.

Advantages
In return, we provide 30 days’ depart each year, entry to a pension scheme, a season ticket mortgage scheme and aggressive salaries. We additionally provide enhanced household pleasant depart, and an on-site nursery on the Mile Finish campus. Additionally, you will work with a pleasant workforce, with private improvement alternatives.

Queen Mary’s dedication to our numerous and inclusive neighborhood is embedded in our appointments processes. Cheap changes can be made at every stage of the recruitment course of for any candidate with a incapacity.

Additional particulars and apply