University of Dundee
Job title:
Postdoctoral Analysis Assistant, College of Life Sciences – UOD1368
Firm
College of Dundee
Job description
Job Data Organisation/Firm
UNIVERSITY OF DUNDEE Analysis Subject
Organic sciences
Chemistry Researcher Profile
Recognised Researcher (R2)
First Stage Researcher (R1)
Established Researcher (R3) Nation
United Kingdom Software Deadline
11 Apr 2024 – 00:00 (UTC) Sort of Contract
Different Job Standing
Full-time Is the job funded by way of the EU Analysis Framework Programme?
Not funded by an EU programme Is the Job associated to employees place inside a Analysis Infrastructure?
No
Provide Description
The College of Life Sciences on the College of Dundee is a world-class educational establishment with a fame for the excellence of its analysis, its prime quality instructing and scholar expertise, and the sturdy impression of its actions outdoors academia. With 900 employees from over 60 international locations worldwide the College offers a dynamic, multi-national, collegiate and numerous setting with state-of-the-art laboratory, expertise and instructing amenities.
We’re in search of an skilled and extremely motivated PDRA with experience in mass spectrometrybased proteomics to work within the analysis laboratory of Professor Angus Lamond. The profitable applicant will be part of a collaborative challenge between the Lamond group in Dundee and Dr Kerrin Small (KCL), which is able to characterise protein expression in human adipose tissue from 1,000 twins. The challenge goals to carry out QTL mapping on the ensuing quantitative peptide, phospho-peptide and protein expression knowledge and to combine these knowledge with different omics and medical knowledge from the TwinsUK cohort.
The publish gives a singular alternative to take part in establishing the primary deep, unbiased description of the human adipose proteome, linking info on protein isoform expression and publish translational modifications, with beforehand generated adipose transcriptomes and deep medical phenotypes generated from the TwinsUK cohort. The publish gives the chance to work with cutting-edge MS instrumentation, together with the newly put in Thermo Scientific Orbitrap Astral Mass Spectrometer.
The place is offered for a interval of 36 months, supported by an MRC Challenge Grant, “Deciphering the position of adipose tissue in frequent metabolic illness through adipose tissue proteomics”.
Your priorities will embrace: Working throughout the Lamond Laboratory:
- Optimise strategies for pattern preparation from human adipose tissue
- Optimise MS workflow for peptide and phosphopeptide evaluation utilizing the Orbitrap Astral
- Analyse not less than 1,000 samples of adipose tissue from the Twins UK cohort
- Carry out computational evaluation to quantify and interpret ensuing MS knowledge
- Work collaboratively with different members of the Lamond and Small laboratories.
Who we’re on the lookout for:
- Ph.D in related science self-discipline with prior coaching in quantitative MS-based proteomics.
- Expertise with pattern preparation workflows for proteomic evaluation and operation of orbitrap MS devices, together with phosphopeptide evaluation workflows.
- Glorious technical skills, significantly in relation to trouble-shooting and optimising pattern preparation and MS evaluation pipelines for quantitative proteomics analyses. Potential to supply prime quality scientific experiences and talk clearly and effectively.
- A powerful theoretical and sensible understanding of protein biochemistry and mass spectrometry.
We’re one of many UK’s main universities, internationally recognised for our experience throughout a spread of disciplines and analysis breakthroughs in a number of areas, together with science, medication, and engineering, amongst many others. Our goal is to remodel lives, regionally and globally, which we do as a group of employees (Skilled Companies and Tutorial Colleges), college students and alumni. Skilled Companies directorates are key to delivering the College technique and driving change throughout the College.
The range of our employees and college students helps to make the College of Dundee a UK college of selection for undergraduate, postgraduate and distance studying. Household pleasant insurance policies, employees networks for BME, Disabled and LGBT employees, membership of Athena SWAN, the ECU Race Equality Constitution and Stonewall as effectively a full vary of incapacity providers, create an pleasant and inclusive place to work.
For casual enquiries please contact Prof Angus Lamond ( )
Necessities
Further Data
Work Location(s)
Variety of gives obtainable 1 Firm/Institute UNIVERSITY OF DUNDEE Nation United Kingdom Metropolis Dundee Metropolis (GB) Geofield
The place to use Web site
Contact Metropolis
Dundee Metropolis (GB)
STATUS: EXPIRED
Anticipated wage
Location
Dundee
Job date
Solar, 17 Mar 2024 04:43:18 GMT
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