Postdoctoral Research Assistant, School of Life Sciences – UOD1368

Job title:

Postdoctoral Analysis Assistant, College of Life Sciences – UOD1368

Firm

Job description

Supply Description

The College of Life Sciences on the College of Dundee is a world-class tutorial establishment with a fame for the excellence of its analysis, its prime quality instructing and scholar expertise, and the sturdy impression of its actions outdoors academia. With 900 workers from over 60 international locations worldwide the College offers a dynamic, multi-national, collegiate and numerous surroundings with state-of-the-art laboratory, expertise and instructing amenities.

We’re looking for an skilled and extremely motivated PDRA with experience in mass spectrometrybased proteomics to work within the analysis laboratory of Professor Angus Lamond. The profitable applicant will be a part of a collaborative challenge between the Lamond group in Dundee and Dr Kerrin Small (KCL), which is able to characterise protein expression in human adipose tissue from 1,000 twins. The challenge goals to carry out QTL mapping on the ensuing quantitative peptide, phospho-peptide and protein expression knowledge and to combine these knowledge with different omics and scientific knowledge from the TwinsUK cohort.

The publish presents a novel alternative to take part in establishing the primary deep, unbiased description of the human adipose proteome, linking data on protein isoform expression and publish translational modifications, with beforehand generated adipose transcriptomes and deep scientific phenotypes generated from the TwinsUK cohort. The publish presents the chance to work with cutting-edge MS instrumentation, together with the newly put in Thermo Scientific Orbitrap Astral Mass Spectrometer.

The place is out there for a interval of 36 months, supported by an MRC Undertaking Grant, “Deciphering the position of adipose tissue in widespread metabolic illness by way of adipose tissue proteomics”.

Your priorities will embrace: Working throughout the Lamond Laboratory:

• Optimise strategies for pattern preparation from human adipose tissue
• Optimise MS workflow for peptide and phosphopeptide evaluation utilizing the Orbitrap Astral
• Analyse no less than 1,000 samples of adipose tissue from the Twins UK cohort
• Carry out computational evaluation to quantify and interpret ensuing MS knowledge
• Work collaboratively with different members of the Lamond and Small laboratories.

Who we’re searching for:

• Ph.D in related science self-discipline with prior coaching in quantitative MS-based proteomics.
• Expertise with pattern preparation workflows for proteomic evaluation and operation of orbitrap MS devices, together with phosphopeptide evaluation workflows.
• Wonderful technical skills, significantly in relation to trouble-shooting and optimising pattern preparation and MS evaluation pipelines for quantitative proteomics analyses. Potential to supply prime quality scientific stories and talk clearly and effectively.
• A powerful theoretical and sensible understanding of protein biochemistry and mass spectrometry.

We’re one of many UK’s main universities, internationally recognised for our experience throughout a spread of disciplines and analysis breakthroughs in a number of areas, together with science, medication, and engineering, amongst many others. Our objective is to rework lives, domestically and globally, which we do as a neighborhood of workers (Skilled Companies and Tutorial Faculties), college students and alumni. Skilled Companies directorates are key to delivering the College technique and driving change throughout the College.

The variety of our workers and college students helps to make the College of Dundee a UK college of selection for undergraduate, postgraduate and distance studying. Household pleasant insurance policies, workers networks for BME, Disabled and LGBT workers, membership of Athena SWAN, the ECU Race Equality Constitution and Stonewall as properly a full vary of incapacity providers, create an fulfilling and inclusive place to work.

For casual enquiries please contact Prof Angus Lamond ( )

Necessities

Further Info

Work Location(s)

Variety of presents out there 1 Firm/Institute UNIVERSITY OF DUNDEE Nation United Kingdom Metropolis Dundee Metropolis (GB) Geofield

The place to use Web site

Contact Metropolis

Dundee Metropolis (GB)

STATUS: EXPIRED

Anticipated wage

Location

Dundee

Job date

Solar, 17 Mar 2024 03:31:40 GMT

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