University of Oxford
Job title:
Postdoctoral Research Associate
Company
University of Oxford
Job description
Location: Department of Biology, South Parks Rd, Oxford, OX1 3RBAbout the roleThe arms race at the plant-pathogen interface is a fascinating field of biology that can deliver important new strategies for crop protection. Within this ERC-funded project, we used chemical proteomics to discover secreted plant proteins of Nicotiana benthamiana that are manipulated by Pseudomonas syringae during infection (e.g. Sueldo et al., New Phytol. 2024) and used artificial intelligence (e.g. Homma et al., Nat. Comm 2023) to predict pathogen proteins that might be responsible for this manipulation. This project aims to elucidate the molecular mechanisms underpinning extracellular manipulation of the host during infection. You will use co-immunoprecipitation to verify predicted protein-protein interactions and establish enzymatic assays and activity-based labelling to demonstrate the effect of target manipulation. You will use reverse genetics to deplete the components from both plant and pathogen to demonstrate their importance in pathogen virulence and plant immunity.About youWe seek an enthusiastic new colleague who has extensive experience in molecular cloning, protein expression and purification, and who is keen to collaborate in an interdisciplinary research team.How to applyApplications should include the application letter, a CV, a list addressing the job criteria, and names of two academic references. Where Covid-19 has resulted in substantial disruption to your work or research outputs, please explain this by providing an additional paragraph in your supporting statement.The University of Oxford is committed to equality and valuing diversity. All applicants will be judged on merit, according to the selection criteria.This post is a 2-year fixed term, full time position.The closing date for applications is 12.00 noon on 02 August 2024.For further inquiries, please contact£36,024 to £39,347 per annum
Expected salary
£36024 – 39347 per year
Location
Oxford
Job date
Sun, 07 Jul 2024 00:11:21 GMT
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