Postdoctoral Research Associate

Job title:

Postdoctoral Research Associate

Company

University of Edinburgh

Job description

Job Description:UE07 – £39,347 – £46,974School of Biological Sciences – Institute of Infection and Immunology ResearchFull Time- 35 hours per weekFixed Term- 1st January 2025 – 31st December 2026The Opportunity:We are looking for a Postdoctoral Research Associate to investigate the mucosal immune and inflammatory response during murine infection with the parasite Schistosoma mansoni, focusing on RNA sequencing, multi-dimensional and multi-omics data analysis, and integration of such with cellular immunology readouts.The specific aim of this position will be to reveal core immune and inflammatory features of the mucosal response to S. mansoni, with a focus on defining the role of macrophages, dendritic cells and CD4+ T cells in induction vs regulation of intestinal and/or pulmonary tissue damage and repair during murine infection with this parasite. Part of this will involve linking sequencing data with immune readouts, microbiota and metabolic data sets, to identify key mechanisms that promote or regulate mucosal inflammation against S. mansoni.This post is advertised as full-time (35 hours per week).Your skills and attributes for success:

• Planning and execution of the research project, under general guidance from the PI
• Experimental work on the mucosal response to S. mansoni, using a range of techniques including murine infection with this parasite, isolation of immune cells from tissues ex vivo, RNAseq, 16S and metagenomic sequencing, and advanced multi-dimensional data analysis and integration
• Presentation and discussion of research findings within and beyond the research group, including via publications, presentation at conferences etc.
• Supervision of students and junior staff working on the project
• Contribute to laboratory organisation and maintenance

As a valued member of our team, you can expect:

• A competitive salary of £39,347 – £46,974
• An exciting, positive, creative, challenging and rewarding place to work.
• To be part of a diverse and vibrant international community.
• Comprehensive Staff Benefits, such as a generous holiday entitlement, a defined benefits pension scheme, staff discounts, family-friendly initiatives, and flexible work options. Check out the full list on our

(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.Championing equality, diversity and inclusionThe University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab).The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa.Key dates to noteThe closing date for applications is 27 September 2024.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.Interviews dates TBC.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:IIIR conducts fundamental research across the areas of immunology, infection, genetics and epidemiology, in order to develop new interventions to control human and animal diseases. The Institute encompasses an exceptional breadth of pathogen research, from viruses to helminth parasites, on a wide platform of scientific approaches from functional genomics to mathematical biology. IIIR’s environment and facilities offer outstanding opportunities for interdisciplinary research into immunology and infection. Our four main themes are: fundamental immunology; immune regulation of disease; molecular biology and genetics of parasites; and host-pathogen population biology. Research is funded by a wide range of sponsors including MRC, the Wellcome Trust, other charities, industry and the European Union.IIIR has strong links with the Institute for Evolutionary Biology, in particular through the Centre for Immunity, Infection and Evolution (http://ciie.bio.ed.ac.uk (supported by the Wellcome Trust)), which promotes collaborations between basic and clinical scientists (through joint projects with the College of Medicine and Veterinary Medicine), between empirical and mathematical scientists, and between immunological and evolutionary biologists.Find our more at https://www.ed.ac.uk/biology/immunology-infection

Expected salary

£39347 – 46974 per year

Location

United Kingdom

Job date

Sat, 31 Aug 2024 22:47:57 GMT

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