University of Edinburgh
Job title:
Postdoctoral Research Associate
Company
University of Edinburgh
Job description
Job Description:Grade UE07: £39,347 – £46,974 per annumCollege of Science and Engineering/School of Biological Sciences/Institute of Cell BiologyFull-time: 35 hours per weekFixed-term: (Sept 2024 – March 2027)We are looking for a post-doctoral level molecular and cell biologist specialising in analysis of gene expression and investigating mutant phenotypes in Cryptococcus neoformans and Schizosaccharomyes pombe.The Opportunity:To conduct research and analysis pertaining to mechanisms of antifungal resistance via chromatin-mediated regulation in both Cryptococcus neoformans and Schizosaccharomyes pombe within the Allshire laboratory; contributing to the development of new ideas, approaches and concepts. To influence the overall direction and management of the research project and to contribute to publishing or otherwise disseminating the outputs of research.Your skills and attributes for success:
- Ability to plan and execution specific elements of research projects, acting under general guidance from the PI.
- Conduct growth, manipulation, and analysis of C. neoformans and S. pombe epigenetic regulation of gene expression using appropriate tools/conditions – developing/modifying tools/conditions when necessary.
- Implement RNA-seq, ChIP-seq and related protocols for analysis of histone PTM distribution and gene expression across the genome of wild-type, mutant and epimutant isolates.
- Ability to collaborate and communicate with other researchers to improve experimental design, implement approaches and analyse data in order to expedite conversion of results obtained into publications.
Click to view a copy of the full (opens new browser tab)As a valued member of our team, you can expect:
- A competitive salary.
- An exciting, positive, creative, challenging and rewarding place to work.
- To be part of a diverse and vibrant international community.
- Comprehensive Staff Benefits, such as a generous holiday entitlement, a defined benefits pension scheme, staff discounts, family-friendly initiatives, and flexible work options. Check out the full list on our
(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.Championing equality, diversity and inclusionThe University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab).The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa.Key dates to noteThe closing date for applications is 17th June 2024.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:The Institute of Cell Biology (ICB) is a world-leading research centre for cell and molecular biology. Our research aims to uncover fundamental mechanisms responsible for the stability, transmission and expression of genetic information in both prokaryotes and eukaryotes, as well as studies of processes underlying microbial physiology and pathogenesis. We work with a wide range of experimental systems including cell culture, bacteria, yeast, Drosophila and mouse.We work closely with other areas of the School and with colleagues in the College of Medicine and Veterinary Medicine, and have particularly strong links with members of the Institute of Structural and Molecular Biology and with SynthSys (the centre for Synthetic & Systems Biology) with whom we have common research interests and many collaborative projects. Facilities include high through-put DNA sequencing, protein production and purification, biophysical and kinetic analysis of proteins, in silico screening for drug leads, proteomics, optical and electron microscopy.ICB incorporates the Wellcome Trust Centre for Cell Biology, a flagship research centre answering fundamental questions relating to cellular function. Our research is funded by, amongst others, BBSRC, CR-UK, European Commission, Gates Foundation, Mayo Foundation, MRC, Royal Society and the Wellcome Trust.To find out more visit https://www.ed.ac.uk/biology/cell-biology
Expected salary
£39347 – 46974 per year
Location
United Kingdom
Job date
Wed, 05 Jun 2024 06:53:07 GMT
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