University of Exeter
Faculty of Health and Life Sciences
This new full-time post is immediately available until 7 august 2026 on a fixed term basis.
Please be aware that you might be requested to occasionally work outside of office hours depending on the nature of the experiments.
This role may be subject to additional background screening.
The Faculty of Health and Life Sciences wishes to recruit a Postdoctoral Research Associate to support the work of Prof Steven West. This Wellcome Trust-funded post is available immediately and for three years. The successful applicant will study the regulation of RNA polymerase II (RNAPII) transcription in human cells. It will focus on the mechanisms of premature transcriptional termination and how these control the expression of genes. The lab has made several interesting and important breakthroughs in this area and the post will build and expand on these. As part of the post, you will receive training/experience in the latest molecular biology methods including CRISPR/Cas9 genome modification, transcriptomic approaches (POINT-seq, mNET-seq, TT-seq, SLAM-seq) and the associated bioinformatic analyses. Specific projects are available to study premature termination pathways that are controlled by ZC3H4 (restrictor) or the Integrator complex. However, candidates are also welcome to come up with their own ideas and will be supported to develop their own projects if they wish to.
The successful applicant will be able to present information on research progress and outcomes, communicate complex information, orally, in writing and electronically and prepare proposals and applications to external bodies.
Applicants will possess a relevant PhD (or be nearing completion) or possess an equivalent qualification/experience in a related field of study and be able to demonstrate sufficient knowledge in the discipline and of research methods and techniques to work within established research programmes. Whilst it would be an advantage to have a background in transcription and/or RNA biology, as well as bioinformatics, this is not essential, and all relevant training can be provided. What is most important, is interest and enthusiasm for the research area and a willingness to learn.
Please ensure you read the Job Description and Person Specification for full details of this role by clicking on the attachment.
What we can offer you
- Freedom (and the support) to pursue your intellectual interests and to work creatively across disciplines to produce internationally exciting research;
- Support teams that understand the University wide research and teaching goals and partner with our academics accordingly;
- An Innovation, Impact and Business directorate that works closely with our academics providing specialist support for external engagement and development;
- Our Exeter Academic initiative supporting high performing academics to achieve their potential and develop their career;
- A beautiful campus set in the heart of stunning Devon.
The University of Exeter
We are a member of the prestigious Russell Group of research-intensive universities and in the top 150 universities in the world (Times Higher Education World University Rankings 2023 and the 2022 Academic Ranking of World Universities released by Shanghai Rankings).
Our research income in recent years means we’re the fastest growing UK Research University with some of the world’s most influential scientists, and we seek to answer some of the most fundamental issues facing humankind today. More than 99% of our research is of international quality and our world-leading research impact is growing faster than any other Russell Group university (2021 Research Excellence Framework). We are using the power of our education and research to create a sustainable, healthy and socially just future. Our shared purpose and vision continually moves us forward to make a difference to our people, our communities, our partners and the world around us. Read about our world leading research on Green Futures and how we are transforming education for a changing world. We are located in a beautiful part of the country and Exeter (a fast growing tech hub) is one of only a few UK cities to have been designated as a UNESCO City of Literature
Our Equality, Diversity and Inclusion Commitment
Whilst all applicants will be judged on merit alone, we particularly welcome applications from groups currently underrepresented within our working community. Reasonable adjustments are available for interviews and workplaces.
With over 30,000 students and 7,000 staff from 150 different countries we offer a diverse and engaging environment where our diversity is celebrated and valued as a major strength. We are committed to creating an inclusive culture where all members of our community are supported to thrive; where diverse voices are heard through our engagement with evidence-based charter frameworks for gender (Athena SWAN and Project Juno for Physics), race equality (Race Equality Charter Mark), LGBTQ+ inclusion (Stonewall Diversity Champion) and as a Disability Confident employer.
For further information please contact Steven West, e-mail [email protected] or telephone (01392) 727458.
The closing date for completed applications is 23 July. Interviews are expected to take place week beginning 14th August.
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