Postdoctoral Research Associate, cryoEM/cryoET software

Job title:

Postdoctoral Research Associate, cryoEM/cryoET software

Company

Diamond Light Source

Job description

FTC untill 31st March 2025About UsDiamond Light Source is the UK’s national synchrotron science facility. By accelerating electrons to near light-speed, Diamond generates brilliant beams of light from infra-red to X-rays which are used for academic and industry research and development across a range of scientific disciplines including structural biology, physics, chemistry, materials science, engineering, earth and environmental sciences.About the RoleWe now have an opportunity for a Postdoctoral Research Associate to join Professor Zhang’s lab at the Electron Bio-Imaging Centre (eBIC), Diamond Light Source, UK to develop new methods in cryoET and subtomogram averaging for in situ structural biology.In situ structural biology by cryoET is a fast-growing field. However, software to push the quality and resolution of tomographic reconstruction is urgently needed. The current existing reconstruction software packages have limitations in refining all 3D spatial parameters, resulting suboptimal reconstruction. We have recently developed a new tilt series alignment algorithm for all 5 spatial parameters at each tilt, which is also performed entirely in Fourier space and vastly increases the processing speed. We are seeking highly motivated scientist to develop this further, including new subtomogram averaging methods in conjunction with our new cryoET data collection schemes.The post is based in eBIC, the UK national cryoEM facility, which provides scientists with state-of-the-art instruments and expertise in cryoEM. Currently eBIC houses four academic Titan Krios, a Talos Arctica, and a Glacios, two cryoFIB/SEM instruments (Scios and Aquilos), and a Leica cryoCLEM for correlative light and electron microscopy ( ).For further information about this role please contact Peijun Zhang ( ).About YouYou should have a PhD degree in structural biology or equivalent and have a demonstrated record of accomplishment in conducting high quality original research. Knowledge and research experience in cryoEM and cryoET, especially in image processing, are essential. Substantial experience in programming and software development is also essential.BenefitsDiamond offers an exceptional benefits package to support staff in achieving a positive work/life balance. This includes 26 days annual leave plus Christmas closure, public holidays, 2 annual volunteering days and flexible working hours. We also offer an excellent defined benefit pension scheme. Staff also have access to a range of amenities on site including a nursery, cafes, a restaurant and sports and leisure facilities. A relocation allowance may also be available where applicable.To ApplyPlease use the online application process to apply and tell us why you believe you are suitable for this role.The initial closing date for applications is 8th December 2024, however applications will be reviewed and interviewed on an ongoing basis until this vacancy is filled.Business AreaScienceFull Time Salary£38,756 to £42,588 (Discretionary range to £48,977)Post TypeFull time / Fixed termClosing Date08/12/2024

Expected salary

£38756 – 42588 per year

Location

United Kingdom

Job date

Fri, 29 Nov 2024 06:49:45 GMT

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