We need to recruit a Postdoctoral Analysis Affiliate at some stage in as much as 24 months for this publish which is out there to start on 1st January 2024.
The undertaking is funded by The European & Growing Nations Scientific Trials Partnership (EDCTP) and the goal of the undertaking might be to review and stop HIV-1 mom to youngster transmission through breastfeeding. Regardless of nice progress in HIV-1 analysis and antiretroviral remedy improvement some two to 5 % of youngsters will purchase the virus through breastfeeding in the course of the preliminary weeks of life.
The research, a scientific trial, will happen in Tanzania and Mozambique and can recruit greater than two thousand pregnant girls. Our position on this undertaking might be to review the viral parameters related to HIV-1 transmission.
We are going to research the viral break-through infections in youngsters regardless of the administration of antiretroviral remedy.
The molecular traits of the virus might be studied which requires expertise in bioinformatics and data of subsequent technology sequence platforms, extra particularly, Oxford Nanopore methodology with proficiency on the related evaluation pipelines.
The goal would be the virus genome sequencing, investigation and evaluation for the presence of mutations conferring resistance to antivirals.
Moreover, the virus envelope protein might be investigated utilizing state-of-the-art pseudo-typed viral particle instruments for its reactivity to broadly neutralising antibodies, with potential future remedy methods recognized. The later work requires data of Cell tradition methodologies with implementation of transfection and transduction of cell strains required for the manufacturing of Pseudo-type virus particles and subsequent testing of immune sera and business antibodies in line with established methodologies and protocols.
The publish might be based mostly within the Division of Scientific An infection, Microbiology and Immunology, one among three departments inside the Institute of An infection, Ecological and Veterinary Sciences (IVES), becoming a member of a extremely dynamic and scientifically productive group, with wonderful publication output and a observe document of fine citizenship and collegiality.
You should have a PhD in a related topic space. This publish is out there till 31 December 2025.
Any candidates who’re nonetheless awaiting their PhD to be awarded must be conscious that if profitable, they are going to be appointed at grade 6, backbone level 30. Upon written affirmation that they’ve been profitable in being awarded their PhD, they are going to be moved onto grade 7, backbone level 31 from the date of their award.
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