Postdoctoral Research Fellow

Job title:

Postdoctoral Research Fellow

Company

University of Edinburgh

Job description

Job Description:UE07 £39,347 – £46,974 per annumCollege of Medicine and Veterinary Medicine / Institute for Regeneration and Repair / Centre for Regenerative MedicineFull-time: 35 hours per weekFixed Term: 20 monthsWe are looking for a postdoctoral researcher to develop novel stem cell gene therapies for childhood neurological diseases. Your main role will be to develop and improve ex vivo stem cell gene therapies for Mucopolysaccharide diseases. Experience of working with mouse disease models and gene or cell therapy is essential.This post is advertised as full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns.The Opportunity:The position offers an ideal opportunity for an enthusiastic, well-motivated postdoctoral researcher, who wants to be part of a programme of research within the laboratory of Professor Brian Bigger. It is ideally suited to a recent PhD graduate. The post holder will lead a project to develop novel ex vivo gene therapies, building on existing work and expertise in the Bigger lab and helping to develop new treatments for devastating childhood dementias such as Sanfilippo disease and Hunter disease. The lab has two gene therapies currently in clinical trial, so this is an opportunity to be at the forefront of translational gene therapy for neurological diseases.Your skills and attributes for success:

• A PhD (achieved or about to be awarded) in neuroscience, cell biology, biochemistry, gene therapy, pharmaceutical sciences or a related haematological discipline.
• Excellent research and methodological skills relevant to the research theme.
• Experience of working with stem cells
• Experience of working with viral vectors, in particular lentivirus.
• Experience of working with animals/personal licence.

Click to view a copy of the full (opens new browser tab)As a valued member of our team, you can expect:

• A competitive salary.
• An exciting, positive, creative, challenging and rewarding place to work.
• To be part of a diverse and vibrant international community.
• Comprehensive Staff Benefits, such as a generous holiday entitlement, a defined benefits pension scheme, staff discounts, family-friendly initiatives, and flexible work options. Check out the full list on our

(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.Championing equality, diversity and inclusionThe University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab).The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa. Please note if the role is offered on a part-time basis, it may result in sponsorship being dependant on a number of factors specific to the successful applicant or the role no longer meeting the Home Office’s criteria for sponsorship.Key notes for applicantsAs part of this application, you are required to upload a cover letter/statement of not more than one page detailing how you meet each of the essential criteria as outlined on the job description and a CV.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.We anticipate that interviews will be held within 2-3 weeks of the advert closing date.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:The Centre for Regenerative Medicine (CRM; Director, Professor Stuart Forbes) brings together world leading basic stem cell research with established clinical excellence to deliver a “bench-to-bedside” approach in addressing the challenges posed by degenerative diseases.CRM is part of the Institute for Regeneration and Repair and housed in a £56m purpose-build building at Edinburgh BioQuarter. It is home to 26 highly interactive research groups working to understand stem cells and their interactions with the tissues in which they are found. Specific research themes include stem cell development and formation of the niche, tissue maintenance and repair, reprogramming of somatic cells back to stem cells (iPS cells) and disease modelling using stem cells. Translational research programmes span four therapeutic targets: brain, blood, liver and heart. Research at CRM involves more than 250 scientists, graduate students and support and ancillary staff, including those providing key central services and resources.Key to the philosophy of the Centre is collaboration with other University Centres and use of Edinburgh’s superb clinical research infrastructure, which enables the application of regenerative biology and medicine to a wide range of biological problems and diseases.

Expected salary

£39347 – 46974 per year

Location

Edinburgh – Midlothian

Job date

Sun, 07 Jul 2024 00:26:48 GMT

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