Postdoctoral Research Fellow

Job title:

Postdoctoral Research Fellow

Company

University of Edinburgh

Job description

Job Description:UE07: £39,347 to £46,974CMVM / Human Genetics UnitFull time: 35 hours per weekFixed term: 3 yearsA postdoctoral researcher is sought for a three-year post in the lab of Prof. Andrew Jackson FRS, to investigate the cellular basis of human genome stability disorders. The purpose of this post is to understand the cellular basis of human genome stability disorders. The successful applicant will investigate how and where endogenous Topoisomerase 1-mediated DNA damage occurs and causes mutagenesis. As well, there will be the opportunity to investigate the downstream consequences and modulators for innate immune activation and clearance of damaged DNA.The Opportunity:A postdoctoral researcher is sought for a three-year post in the lab of Prof. Andrew Jackson FRS, to investigate the cellular basis of human genome stability disorders. The purpose of this post is to understand the cellular basis of human genome stability disorders. The successful applicant will investigate how and where endogenous Topoisomerase 1-mediated DNA damage occurs and causes mutagenesis. As well, there will be the opportunity to investigate the downstream consequences and modulators for innate immune activation and clearance of damaged DNA.The post-holder will be part of a multidisciplinary team, working in a cross-disciplinary environment that addresses both fundamental cellular processes and disease mechanisms. The research group is internationally diverse and strongly competitive with 12 papers published in Cell and Nature journals in the last 10 years.This post is full-time (35 hours per week); however, we are open to considering flexible working patterns. We are also open to considering requests for hybrid working (on a non-contractual basis) that combines a mix of remote and regular on-campus working.Click to view a copy of the full job descriptionAs a valued member of our team you can expect:

• A competitive salary of £39,347 – £46,974
• An exciting, positive, creative, challenging and rewarding place to work.
• To be part of a diverse and vibrant international community
• Comprehensive Staff Benefits, such as a generous holiday entitlement, a defined benefits pension scheme, staff discounts, family-friendly initiatives, and flexible work options. Check out the full list on our

(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefitsChampioning equality, diversity and inclusionThe University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab)The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa.Key dates to noteThe closing date for applications is 29 July 2024.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:A deep understanding of human genome function – particularly for the non-coding genome – is an outstanding grand challenge. Our mission is to discover how our genome controls the function of molecules, cells and tissues, in health and disease, connecting human genetic variation to phenotype.Multidisciplinary HGU research programs embrace genetic, computational, biochemical, cellular, model organism and clinical approaches, to gain meaningful insights across scales and dynamic processes, with cross-cutting themes in 4D Cellular Medicine and Genome Interpretation.To find out more visitThe MRC Human Genetics Unit is part of the Institute of Genetics and Cancer (IGC). This partnership with CRUK Edinburgh Centre and Centre for Genomic and Experimental Medicine Centre aims to understand development and disease by using the latest developments in genetic, genomic, cellular and clinical science. The partnership provides access to state of the art scientific facilities, scientific infrastructure and business support, including on site Advanced Imaging Resource, Animal Model support, Bioinformatics Analysis Core, DNA sequencing, Flow Cytometry, Mass Spectrometry, HTPU microarray. The IGC also offers a highly collegial environment with excellent local career development support, active social, wellbeing and sustainability related groups making it a very desirable and supportive working environment.To find out more visit

Expected salary

£39347 – 46974 per year

Location

Edinburgh – Midlothian

Job date

Wed, 17 Jul 2024 06:40:22 GMT

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