Postdoctoral Research Fellow

Job title:

Postdoctoral Research Fellow

Company

University of Edinburgh

Job description

Job Description:Grade UE07: £40,247 to £47,874 per annumCMVM / Institute for Regeneration and Repair / Centre for Inflammation ResearchFull-time: 35 hours per weekFixed Term: 2 years in first instance, with potential for extensionWe are looking for a motivated postdoctoral research fellow with excellent tissue-culture skills to join a project focusing on understanding how rare genetic mutations cause lung inflammation, and how this can be targeted therapeutically.This post is advertised as full-time (35 hours per week); however, we are open to considering flexible working patterns.The Opportunity:This post is part of the newly-funded LifeArc Centre for Rare Respiratory Disease. The post holder will be a valuable part of a multi-university Consortium aimed at advancing Rare Respiratory Disease research and therapeutics. The successful candidate will further develop model systems, such as lung organoids, to characterise immune responses of a genetic lung disease which predisposes to activation of the STING immune pathway.Your skills and attributes for success:

• Appropriate degree (e.g., Immunology or Genetics or another area of Biology relevant to the project) with relevant post-graduate research experience and accumulated knowledge
• A PhD or equivalent professional qualification and/or experience in the field of Immunology, Molecular Genetics, Developmental and Stem Cell Biology or other area of Biology relevant to the project. It is possible for the PhD to be completed within 3 months of interview date
• Prior experience in sterile tissue culture
• Prior experience in a “wet-lab” research environment
• Accuracy and attention to detail when carrying out experiments

Click to view a copy of the full (opens new browser tab)As a valued member of our team, you can expect:

• A competitive salary.
• An exciting, positive, creative, challenging and rewarding place to work.
• To be part of a diverse and vibrant international community.
• Comprehensive Staff Benefits, such as a generous holiday entitlement, a defined benefits pension scheme, staff discounts, family-friendly initiatives, and flexible work options. Check out the full list on our

(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.Championing equality, diversity and inclusionThe University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab).The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa.Key notes for applicantsAs part of this application, you are required to upload a cover letter/statement of not more than one page detailing how you meet each of the essential criteria as outlined on the job description and a CV.The closing date for applications is 5 December 2024.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.We anticipate that interviews will be held within 2-3 weeks of the advert closing date.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:The Centre for Inflammation Research (CIR; Director, Professor David Dockrell) leverages peer-reviewed interdisciplinary research programmes and focussed collaboration, to characterise mechanisms of acute and chronic inflammation. CIR aims to characterise what promotes health at the molecular level in order to prevent the harmful consequences of inflammation in clinical medicine. Effort is targeted at: inhibiting the initiation of inflammation by blocking specific molecular triggers and by modulating cellular and tissue responses resulting in organ dysfunction; finding new approaches to modulate established inflammatory responses to limit tissue injury; and promoting safe resolution of inflammation to restore healthy structure and function of tissue.The CIR has a broad interest in inflammatory disease in a range of tissues including in the lungs, kidney, liver, pancreas, bowel, bone, joints, skin, heart and brain. There is in-depth analysis of stimuli that induce or modify inflammation with detailed programmes considering the role of sex, development, auto-immunity, infection and other environmental influences. Importantly, the principles derived will have ready application to inflammatory and reparatory responses in virtually all physiological and pathological settings, including cancer and infection (not least COVID-19). Translation is aided by a commitment to novel diagnostic and imaging modalities and our proximity to patient groups and healthy volunteers in the Royal Infirmary, Edinburgh.Our research aims align closely with the vision of IRR and other centres within IRR, to promote human health through in-depth understanding of tissue regeneration and repair, while developing a multi-pronged translational programme to effect therapeutic innovation in this area. IRR is located on the BioQuarter Campus, Edinburgh.

Expected salary

£40247 – 47874 per year

Location

Edinburgh – Midlothian

Job date

Sat, 16 Nov 2024 02:28:13 GMT

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