Postdoctoral Research Fellow

Job title:

Postdoctoral Research Fellow

Company

University of Edinburgh

Job description

Job Description:Grade UE07: £40,247 – £47,874 per annumCMVM / Institute for Regeneration and Repair / Centre for Inflammation ResearchFull-time: 35 hours per weekFixed Term: 2 yearsWe are looking for a driven and enthusiastic Quantitative Geneticist Research Fellow to help deliver a large-scale single cell molecular QTL discovery programme supported by £5M of UKRI funding as part of the Edinburgh Molecular Mechanisms Cluster.This post is advertised as full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns. We are also open to considering requests for hybrid working (on a non-contractual basis) that combines a mix of remote and regular on-campus working.The Opportunity:We have shown that molecular quantitative trait loci (molQTL) can reveal specific molecular mediators, cell types and states underlying disease, and lead directly to new, effective therapies. The Molecular Mechanisms Cluster (MMC) will systematically study single cells from primary human tissues, across a range of perturbation states, to reveal the molecular con- sequences of disease-associated genetic variation. This cross-cutting project combines precise laboratory techniques with advanced computational modelling.This post will be based at the Baillie Gifford Pandemic Science Hub (PSH: /) at the Institute for Regeneration and Repair.Your skills and attributes for success:

• A PhD (or near completion) or equivalent professional qualification and/or experience in the field of genetics, bioinformatics, computational biology
• Strong expertise in performing eQTL analyses and/or integrating large-scale genetic and transcriptomic datasets (e.g., GWAS, RNA-seq)
• Proficiency in programming languages such as R or Python and experience with bioinformatics tools
• Strong planning and organising skills
• Excellent written and verbal communication skills with ability to build rapport with colleagues and collaborators.

Click to view a copy of the full (opens new browser tab)As a valued member of our team, you can expect:An exciting, positive, creative, challenging and rewarding place to work. We give you support, nurture your talent and reward success. You will benefit from a competitive reward package and a wide range of staff benefits, which includes a generous holiday entitlement, a defined benefits pension scheme, staff discounts, family-friendly initiatives, flexible working and much more. Click to access our (opens new browser tab) for further information and use our reward calculator to find out the total value of pay and benefits provided.The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University, you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab)Key notes for applicantsAs part of this application, you are required to upload a cover letter/statement of not more than one page detailing how you meet each of the essential criteria as outlined on the job description and a CV.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.We anticipate that interviews will be held within 2-3 weeks of the advert closing date.The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:The Centre for Inflammation Research (CIR; Director, Professor David Dockrell) leverages peer-reviewed interdisciplinary research programmes and focussed collaboration, to characterise mechanisms of acute and chronic inflammation. CIR aims to characterise what promotes health at the molecular level in order to prevent the harmful consequences of inflammation in clinical medicine. Effort is targeted at: inhibiting the initiation of inflammation by blocking specific molecular triggers and by modulating cellular and tissue responses resulting in organ dysfunction; finding new approaches to modulate established inflammatory responses to limit tissue injury; and promoting safe resolution of inflammation to restore healthy structure and function of tissue.The CIR has a broad interest in inflammatory disease in a range of tissues including in the lungs, kidney, liver, pancreas, bowel, bone, joints, skin, heart and brain. There is in-depth analysis of stimuli that induce or modify inflammation with detailed programmes considering the role of sex, development, auto-immunity, infection and other environmental influences. Importantly, the principles derived will have ready application to inflammatory and reparatory responses in virtually all physiological and pathological settings, including cancer and infection (not least COVID-19). Translation is aided by a commitment to novel diagnostic and imaging modalities and our proximity to patient groups and healthy volunteers in the Royal Infirmary, Edinburgh.Our research aims align closely with the vision of IRR and other centres within IRR, to promote human health through in-depth understanding of tissue regeneration and repair, while developing a multi-pronged translational programme to effect therapeutic innovation in this area. IRR is located on the BioQuarter Campus, Edinburgh.

Expected salary

£40247 – 47874 per year

Location

Edinburgh – Midlothian

Job date

Sat, 08 Feb 2025 02:46:01 GMT

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