Postdoctoral Research Fellow

Job title:

Postdoctoral Research Fellow

Company

University of Edinburgh

Job description

Job Description:Grade UE07: £40,497 to £48,149 per annumCentre for Inflammation Research / Institute for Regeneration and Repair / Deanery of Clinical SciencesFull time: 35 hours per weekFixed term: for 9 monthsThe Opportunity:We are looking for a Postdoctoral Research Fellow with expertise in assessing the immune system during organ regeneration in vivo to join our team. The research fellow will dissect the mechanisms of CD4 T-cells in affecting liver epithelium regeneration. This research will primarily employ animal models of liver disease and in vitro cultures.The post holder should have expertise in epithelial and immune cell isolation and culture, flow cytometry, basic tissue culture and molecular biology techniques. Prior experience with organoid culture, complex microscopy, spectral flow cytometry would be advantageous. Applicants should be able to demonstrate prior research success; for example, through publications/pre-prints, presentations at conferences and relevant academic prizes/travel awards. We provide an inspirational environment for you to pursue your personal research aims.Your skills and attributes for success:

• A PhD (or will shortly attain) in, molecular or cell biology, regenerative medicine, immunology, or a related discipline.
• Home Office Personal License (PIL)
• Practical experience with bright-field and confocal microscopy, immunofluorescence labelling and molecular imaging.
• Tissue sectioning and histological / immunohistochemical techniques.
• Extensive experience of operating spectral flow cytometry (e,g: Cytek Aurora system)

Click to view a copy of the full (opens new browser tab).Application InformationPlease ensure you include the following documents in your application:– CV– Cover letterAs a valued member of our team, you can expect:

• A competitive salary.
• An exciting, positive, creative, challenging and rewarding place to work.
• To be part of a diverse and vibrant international community.
• Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our

(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.Championing equality, diversity and inclusionThe University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University, you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab)On this occasion the University will not consider applicants requiring sponsorship for this role. International workers will therefore only be able to take up this role if they can demonstrate an alternative right to work in the UK.Key dates to noteThe closing date for applications is 13 March 2025.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:The Centre for Inflammation Research (CIR; Director, Professor David Dockrell) leverages peer-reviewed interdisciplinary research programmes and focussed collaboration, to characterise mechanisms of acute and chronic inflammation. CIR aims to characterise what promotes health at the molecular level in order to prevent the harmful consequences of inflammation in clinical medicine. Effort is targeted at: inhibiting the initiation of inflammation by blocking specific molecular triggers and by modulating cellular and tissue responses resulting in organ dysfunction; finding new approaches to modulate established inflammatory responses to limit tissue injury; and promoting safe resolution of inflammation to restore healthy structure and function of tissue.The CIR has a broad interest in inflammatory disease in a range of tissues including in the lungs, kidney, liver, pancreas, bowel, bone, joints, skin, heart and brain. There is in-depth analysis of stimuli that induce or modify inflammation with detailed programmes considering the role of sex, development, auto-immunity, infection and other environmental influences. Importantly, the principles derived will have ready application to inflammatory and reparatory responses in virtually all physiological and pathological settings, including cancer and infection (not least COVID-19). Translation is aided by a commitment to novel diagnostic and imaging modalities and our proximity to patient groups and healthy volunteers in the Royal Infirmary, Edinburgh.Our research aims align closely with the vision of IRR and other centres within IRR, to promote human health through in-depth understanding of tissue regeneration and repair, while developing a multi-pronged translational programme to effect therapeutic innovation in this area. IRR is located on the BioQuarter Campus, Edinburgh.

Expected salary

£40497 – 48149 per year

Location

Edinburgh – Midlothian

Job date

Sat, 01 Mar 2025 06:36:46 GMT

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