Postdoctoral Research Fellow

Job title:

Postdoctoral Research Fellow

Company

University of Edinburgh

Job description

Job Description:Grade UE07: £40,497 – £48,149 per annumCMVM / Institute for Regeneration and Repair / Centre for Inflammation ResearchFull-time: 35 hours per weekFixed Term: 2 yearsWe are looking for a Postdoctoral Research Fellow in Organic/Medicinal ChemistryThis post is advertised as full-time (35 hours per week).The Opportunity:A postdoctoral position in drug development for pulmonary microdosing trials is funded by the EPSRC-backed MicroTex Hub, a multidisciplinary initiative combining robotics, AI, chemistry, physics, biology, and clinical medicine to rapidly test treatments for pulmonary inflammation and infection. Based at the Baillie Gifford Pandemic Science Hub, MicroTex unites scientists, clinicians, and researchers to accelerate drug discovery. The candidate will synthesize new and known drugs, develop formulations for microdosing, ensure bench-to-bedside translation, contribute to research strategy, and support commercialization and dissemination of findings.Your skills and attributes for success:

• Excellent organic chemistry skills, varied experience in the mg to g scale synthesis of small organic pharmacophore.
• Experience in Solid Phase Peptide Synthesis and/or fluorescent labelling.
• Extensive knowledge of analytical techniques relevant to organic synthesis, such as but not limited to: NMR, Mass Spectrometry, absorption and emission spectrophotometry, HPLC, LCMS.
• Problem-solving and troubleshooting experience with standard chemistry equipment.
• Direct experience in working in multidisciplinary teams.

Click to view a copy of the full (opens new browser tab)As a valued member of our team, you can expect:

• A competitive salary.
• An exciting, positive, creative, challenging and rewarding place to work.
• To be part of a diverse and vibrant international community.
• Comprehensive Staff Benefits, such as a generous holiday entitlement, a defined benefits pension scheme, staff discounts, family-friendly initiatives, and flexible work options. Check out the full list on our

(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits.Championing equality, diversity and inclusionThe University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University, you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab)The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa.Key notes for applicantsThe closing date for applications is 31 March 2025.As part of this application, you are required to upload a cover letter/statement of not more than one page detailing how you meet each of the essential criteria as outlined on the job description and a CV. These items should be uploaded as one single combined document in either PDF or Word format.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.We anticipate that interviews will be held within 2-3 weeks of the advert closing date.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:The Centre for Inflammation Research (CIR; Director, Professor David Dockrell) leverages peer-reviewed interdisciplinary research programmes and focussed collaboration, to characterise mechanisms of acute and chronic inflammation. CIR aims to characterise what promotes health at the molecular level in order to prevent the harmful consequences of inflammation in clinical medicine. Effort is targeted at: inhibiting the initiation of inflammation by blocking specific molecular triggers and by modulating cellular and tissue responses resulting in organ dysfunction; finding new approaches to modulate established inflammatory responses to limit tissue injury; and promoting safe resolution of inflammation to restore healthy structure and function of tissue.The CIR has a broad interest in inflammatory disease in a range of tissues including in the lungs, kidney, liver, pancreas, bowel, bone, joints, skin, heart and brain. There is in-depth analysis of stimuli that induce or modify inflammation with detailed programmes considering the role of sex, development, auto-immunity, infection and other environmental influences. Importantly, the principles derived will have ready application to inflammatory and reparatory responses in virtually all physiological and pathological settings, including cancer and infection (not least COVID-19). Translation is aided by a commitment to novel diagnostic and imaging modalities and our proximity to patient groups and healthy volunteers in the Royal Infirmary, Edinburgh.Our research aims align closely with the vision of IRR and other centres within IRR, to promote human health through in-depth understanding of tissue regeneration and repair, while developing a multi-pronged translational programme to effect therapeutic innovation in this area. IRR is located on the BioQuarter Campus, Edinburgh.

Expected salary

£40497 – 48149 per year

Location

Edinburgh – Midlothian

Job date

Wed, 05 Mar 2025 04:51:43 GMT

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