Postdoctoral Research Fellow

Job title:

Postdoctoral Research Fellow

Company

University of Edinburgh

Job description

Job Description:Grade: UE07: £40,497 to £48,149 per annum, pro rataCollege of Medicine & Veterinary Medicine/The Roslin InstituteFull-time: 35 hours per weekFixed term: 12 monthsWe are looking for a Research Fellow to help deliver a large-scale single cell molecular QTL discovery programme supported by £5M of UKRI funding as part of the Edinburgh Molecular Mechanisms Cluster.This 1-year post will be based at the Roslin Institute and the Pandemic Science Hub (PSH; ) at the Institute for Regeneration and Repair.This post is full-time (35 hours per week); however, we are open to considering part-time or flexible working patterns.We have shown that molecular quantitative trait loci (molQTL) can reveal specific molecular mediators, cell types and states underlying disease, and lead directly to new, effective therapies. The Molecular Mechanisms Cluster (MMC) will systematically study single cells from primary human tissues, across a range of perturbation states, to reveal the molecular con- sequences of disease-associated genetic variation. This cross-cutting project combines precise laboratory techniques with advanced computational modelling.The holder of this post will conduct laboratory studies using ex vivo clinical samples to help map molQTL in these disease-relevant clinical tissues.Ref:Pairo-Castineira, E. et al. Nature 1-15 (2023)Pairo-Castineira E, Rawlik K, Clohisey S et al. Nature 591, 92-98 (2021)Abani, O. et al. The Lancet 400, 359-368 (2022)Your skills and attributes for success:

• PhD in Molecular Genetics, Cell Biology or a related subject.
• Experienced in primary tissue culture.
• Excellent organisation and administration skills.
• Proven ability to reliably deliver quality outputs in a timely and efficient manner.
• Ability to communicate effectively both orally and in writing across different disciplines.

Click to view a copy of the full (opens new browser tab)Application Information:Please ensure you include the following documents in your application:

• CV
• Cover letter

As a valued member of our team you can expect:

• A competitive salary
• An exciting, positive, creative, challenging and rewarding place to work.
• To be part of a diverse and vibrant international community
• Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our

(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefitsChampioning equality, diversity and inclusion:The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab).On this occasion the University will not consider applicants requiring sponsorship for this role. International workers will therefore only be able to take up this role if they can demonstrate an alternative right to work in the UK.Key dates to note:The closing date for applications is 31 March 2025.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:The Roslin Institute is a world-leading centre for animal bioscience research and has a distinctive niche within the UK National Institutes of Bioscience, supported strategically by the Biotechnology and Biological Sciences Research Council (BBSRC). The Institute moved to a new £60M state-of-the-art building at the Easter Bush Campus in 2011, which is now occupied by > 670 people including ~ 65 Group Leaders and Career Track Fellows, other research and support staff, students and visitors and ~90 staff from Scotland’s Rural College. The Institute has a vibrant programme of postgraduate research, with 176 PhD students registered at the time of writing. Research at the Institute is organised across three research divisions (Genetics & Genomics, Infection & Immunity and Developmental Biology) and three Institute Strategic Programmes (BBSRC funded from 2017-2022) that integrate many disciplines (Blueprints for Healthy Animals, Control of Infectious Diseases and Improving Animal Productivity & Welfare). Crosscutting themes in Epidemiology and Population Health and in Clinical Sciences link research at the Institute to clinical activities in the Royal (Dick) School of Veterinary Studies and support the research activities of clinical academic staff. In the most recent Research Excellence Framework (REF 2014), a joint submission from The Royal (Dick) School of Veterinary Studies, The Roslin Institute and Scotland’s Rural College was ranked 1st by research power (volume x quality) in the category of Agriculture, Veterinary and Food Science.Over £200M has been invested in physical infrastructure at Easter Bush since 2008, including recently in the National Avian Research Facility and the Charnock Bradley Building, which houses the Roslin Innovation Centre – an incubator space for agritech start-up companies and spin out companies to commercialise the Institute’s intellectual property. Investments continue, as the Institute is a major partner in the new Agri-Tech Centre for Innovation Excellence in Livestock, which together with the University, funds the construction of a £25 M Large Animal Research and Imaging Facility. The Centre for Tropical Livestock Genetics and Health, primed by investment from the Gates Foundation and Department for International Development, aims to unlock the genetic potential of farmed animals by dissecting genotype-by-environment interactions to sustainably improve animal productivity in low- and middle-income countries.The Institute’s income exceeds £30M p.a., around 50% of which derives from the BBSRC via strategic and competitive funding. Our focus on improving farming systems, animal productivity and welfare, and the control of animal and zoonotic diseases is key to delivery of the BBSRC’s strategic priorities for Agriculture & Food Security, Veterinary Vaccinology and Bioscience for Health. This research is expedited by extensive interactions with industry, including via ongoing platform agreements with major animal breeding and pharmaceutical companies. The addition of our own £15M equity-funded commercialisation vehicle, Roslin Technologies Ltd, will accelerate translation of research at the Institute in the years to come. The Institute holds a prestigious Athena SWAN Gold award in recognition of our commitment to advance the representation of women in science.Further details of the research conducted at the Institute can be found at https://www.ed.ac.uk/roslin

Expected salary

£40497 – 48149 per year

Location

Edinburgh – Midlothian

Job date

Wed, 19 Mar 2025 08:24:15 GMT

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