Postdoctoral Research Fellow (Computational Biologist)

College of Well being and Life Sciences

This new full-time put up is obtainable instantly till 30 April 2027 on a fixed-term foundation.

The put up

The College needs to recruit a Postdoctoral Analysis Fellow to steer a programme of computational modelling and ‘omics evaluation of the regulatory community dynamics of mammalian pluripotency. This Medical Analysis Council and European Analysis Council funded put up within the group of Professor Austin Smith is obtainable instantly. The position holder will develop a programme of computational analysis and supporting bioinformatics analyses to delineate developmental trajectories, uncover gene regulatory networks dynamics, and delineate cell destiny transition paths.

You’ll work primarily with single cell NGS information from stem cell self-renewal, differentiation and perturbation research, from pure embryos, and from embryoid fashions. Research will embody comparative analyses between human, non-human primates and different mammals, utilizing stem cells and embryos. You’ll create and implement algorithms, evaluation strategies, visualisation instruments and machine studying approaches to interrogate multimodal ‘omics datasets. You’ll create mathematical and/or computational fashions of the pluripotency gene regulatory community and of cell destiny transitions that can iteratively inform experimental analyses.

You’ll have scope to develop your individual analysis and to oversee challenge college students. Additionally, you will collaborate with moist lab researchers within the group and can have the chance to carry out your individual laboratory experiments if applicable.

Prior data in stem cell or developmental biology will not be important, however expertise in working intently with experimental researchers is important.

About you

The profitable applicant will have the ability to develop analysis aims, tasks and proposals; establish sources of analysis funding and contribute to the method of securing funds, and make shows at conferences and different occasions.

Candidates will possess a related PhD or equal qualification/expertise in mathematical, computational, or programs biology, or in bioinformatics. The profitable applicant can be a nationally recognised authority and possess ample specialist data within the self-discipline to develop analysis programmes and methodologies. The profitable applicant can even have the ability to work collaboratively, supervise the work of others and act as crew chief as required. Candidates can have analysis experience in high-throughput information evaluation with competence in a UNIX/Linux setting and programming/scripting language.

You’ll have a great understanding of statistics. You’ll have expertise in subsequent technology sequencing pipelines, together with transcriptomics, chromatin accessibility and single cell analyses. You need to have a common understanding of molecular cell biology and have the ability to work in productive partnerships with experimental researchers. Particular data of stem cell or developmental biology will not be required, however you’ll be accustomed to organic information and be motivated to analyse and mannequin organic processes.

Please make sure you learn the Job Description and Particular person Specification for full particulars of this position.

What we will give you

• Freedom (and the assist) to pursue your mental pursuits and to work creatively throughout disciplines to supply internationally thrilling analysis;
• Assist groups that perceive the College extensive analysis and instructing objectives and associate with our teachers accordingly
• An Innovation, Influence and Enterprise directorate that works intently with our teachers offering specialist assist for exterior engagement and improvement
• Our Exeter Tutorial initiative supporting excessive performing teachers to realize their potential and develop their profession

• An attractive campus set within the coronary heart of gorgeous Devon.

The College of Exeter

We’re a member of the celebrated Russell Group of research-intensive universities and within the high 200 universities on the earth (Occasions Greater Schooling World College Rankings 2024 and QS World College Rating 2024).  We mix world-class instructing with world-class analysis, reaching a Gold score within the Educating Excellence Framework Award 2023, underpinned by Gold scores for Scholar Expertise and Scholar Outcomes.

Our world-leading analysis impression has grown greater than another Russell Group college in recent times, and we’re house to among the world’s most influential researchers, in search of to reply among the most basic points dealing with humankind immediately. Greater than 99 p.c of our analysis is of worldwide high quality and 47 p.c is world-leading (2021 Analysis Excellence Framework).

We encourage proactive engagement with business, enterprise and neighborhood companions to reinforce the impression of analysis and training and enhance the employability of our college students. Examine our world main analysis – Inexperienced Futures and the way we’re remodeling training for a altering world. We’re positioned in a stupendous a part of the nation and Exeter (a quick rising tech hub) is one in all only some UK cities to have been designated as a UNESCO Artistic Metropolis

Our Equality, Range and Inclusion Dedication

We’re dedicated to making sure affordable changes can be found for interviews and workplaces.

While all candidates can be judged on benefit alone, we notably welcome purposes from teams presently underrepresented inside our working neighborhood. 

With over 30,000 college students and seven,000 workers from 150 totally different international locations we provide a various and interesting setting the place our range is widely known and valued as a significant power. We’re dedicated to creating an inclusive tradition the place all members of our neighborhood are supported to thrive; the place various voices are heard via our engagement with evidence-based constitution frameworks for gender (Athena SWAN and Mission Juno for Physics), race equality (Race Equality Constitution Mark), LGBTQ+ inclusion (Stonewall Range Champion) and as a Incapacity Assured employer.

Additional info

For additional info please contact Professor Austin Smith, e-mail [email protected]