Postdoctoral Research Fellow (Computational Biologist)

This new full-time publish is on the market instantly till 30 April 2027 on a fixed-term foundation.

The publish
The College needs to recruit a Postdoctoral Analysis Fellow to guide a programme of computational modelling and ‘omics evaluation of the regulatory community dynamics of mammalian pluripotency. This Medical Analysis Council and European Analysis Council funded publish within the group of Professor Austin Smith is on the market instantly. The position holder will develop a programme of computational analysis and supporting bioinformatics analyses to delineate developmental trajectories, uncover gene regulatory networks dynamics, and delineate cell destiny transition paths.

You’ll work primarily with single cell NGS knowledge from stem cell self-renewal, differentiation and perturbation research, from pure embryos, and from embryoid fashions. Research will embrace comparative analyses between human, non-human primates and different mammals, utilizing stem cells and embryos. You’ll create and implement algorithms, evaluation strategies, visualisation instruments and machine studying approaches to interrogate multimodal ‘omics datasets. You’ll create mathematical and/or computational fashions of the pluripotency gene regulatory community and of cell destiny transitions that can iteratively inform experimental analyses.

You’ll have scope to develop your personal analysis and to oversee venture college students. Additionally, you will collaborate with moist lab researchers within the group and can have the chance to carry out your personal laboratory experiments if acceptable.

Prior data in stem cell or developmental biology shouldn’t be important, however expertise in working carefully with experimental researchers is important.

About you
The profitable applicant will be capable of develop analysis targets, initiatives and proposals; establish sources of analysis funding and contribute to the method of securing funds, and make displays at conferences and different occasions.

Candidates will possess a related PhD or equal qualification/expertise in mathematical, computational, or programs biology, or in bioinformatics. The profitable applicant shall be a nationally recognised authority and possess adequate specialist data within the self-discipline to develop analysis programmes and methodologies. The profitable applicant will even be capable of work collaboratively, supervise the work of others and act as staff chief as required. Candidates can have analysis experience in high-throughput knowledge evaluation with competence in a UNIX/Linux setting and programming/scripting language. You’ll have an excellent understanding of statistics. You’ll have expertise in subsequent technology sequencing pipelines, together with transcriptomics, chromatin accessibility and single cell analyses. You need to have a common understanding of molecular cell biology and be capable of work in productive partnerships with experimental researchers. Particular data of stem cell or developmental biology shouldn’t be required, however you can be acquainted with organic knowledge and be motivated to analyse and mannequin organic processes.

Please make sure you learn the Job Description and Individual Specification for full particulars of this position.

The College of Exeter
We’re a member of the celebrated Russell Group of research-intensive universities and within the high 200 universities on the earth (Occasions Greater Training World College Rankings 2024 and QS World College Rating 2024).  We mix world-class instructing with world-class analysis, attaining a Gold ranking within the Instructing Excellence Framework Award 2023, underpinned by Gold rankings for Scholar Expertise and Scholar Outcomes.

Additional info
For additional info please contact Professor Austin Smith, e-mail [email protected]