Postdoctoral Research Scientist

Job title:

Postdoctoral Analysis Scientist

Firm

College of Oxford

Job description

Postdoctoral Analysis Scientist
Division of Physiology, Anatomy and Genetics, Sherrington Constructing, Parks Street, Oxford, OX1 3PT

Fastened-term till 30/04/2027, Full-time

The Cragg lab alongside different teams inside Oxford (Wade-Martins and Magill), London (Kittler) and Germany (Liss) are conducting a collaborative Wellcome funded analysis mission to discover the physiological roles of Ca2+ in dopamine transmission to achieve insights into the possibly poisonous roles of Ca2+ in Parkinson’s illness.

This mission will exploit state-of-the-art instruments to grasp the roles of Ca2+ inflow, storage and signalling inside dopamine axons in wild-type animal fashions of Parkinson’s. This mission will examine the Ca2+ biology throughout striatal territories to enhance our understanding of the function of Ca2+ in well being and illness. Our lately printed knowledge means that the roles of voltage-gated Ca2+ channels are dynamically regulated throughout striatal territories in a fashion that correlates with threat elements of Parkinson’s [REF].

On this mission we’ll develop a greater understanding of the downstream coupling of Ca2+ to mitochondrial operate to higher perceive the selective vulnerability of a subset of DA neurons in Parkinson’s, and probably determine druggable targets that might neuroprotective potential within the therapy of Parkinson’s. We are actually in search of to nominate a Postdoctoral Analysis Scientist with a powerful curiosity in Ca2+ biology to hitch us as a part of this thrilling collaboration.

Duties embrace contributing to overseeing the administration and genotyping of animal mannequin colonies and parkinsonian fashions; adapting current and creating new scientific strategies and experimental protocols; testing hypotheses and analysing scientific knowledge from a wide range of sources, reviewing and refining working hypotheses as acceptable; contributing concepts for brand new analysis initiatives and creating concepts for producing analysis revenue.

You’ll have a powerful background in electrophysiological and/or electrochemical and/or photometry strategies, to research neural circuits or synapses of the central nervous system. Candidates should maintain, or be near completion of, a PhD/DPhil in a related space of neurobiological analysis.

The mounted time period publish is offered instantly. The publish will likely be based mostly in The Division of Physiology Anatomy & Genetics, Sherrington Constructing, Parks Street, Oxford, OX1 3PT

Casual enquiries could also be directed to the DPAG HR Group – hr@dpag.ox.ac.uk / Professor Stephanie Cragg -stephanie.cragg@dpag.ox.ac.uk

Deadline for purposes is noon on 12/04/2024.

Interviews are more likely to be held on the week commencing 29/04/2024.

Purposes are significantly welcome from ladies, black and minority ethnic candidates who’re under-represented in tutorial posts in Oxford.

Whereas this can be a full-time function, we welcome purposes from people who want to be thought-about for part-time working or different versatile working preparations.

We, as a Division and Neighborhood, will likely be thoughtful and welcoming of all individuals, no matter age, incapacity, gender reassignment, marriage and civil partnership, being pregnant and maternity, race, faith or perception, intercourse, sexual orientation, gender identification, and socio-economic background. We acknowledge societal inequalities and the way these affect us, and people round us, personally and professionally. – DPAG Assertion of Inclusion
Contact Individual : HR Group Emptiness ID : 171664
Contact Telephone : 01865272468 Closing Date & Time : 12-Apr-2024 12:00
Pay Scale : STANDARD GRADE 7 Contact E mail :
Wage (£) : 36024 – 41732

Anticipated wage

Location

Oxford

Job date

Fri, 15 Mar 2024 23:01:13 GMT

To assist us monitor our recruitment effort, please point out in your e mail/cowl letter the place (globalvacancies.org) you noticed this job posting.