Postdoctoral researcher in Single-Molecule Imaging in Living Cells

Job title:

Postdoctoral researcher in Single-Molecule Imaging in Residing Cells

Firm

College of Oxford

Job description

Postdoctoral researcher in Single-Molecule Imaging in Residing Cells
Division of Physics, Kavli Institute for Nanoscience Discovery

Mounted time period for 48 months

We’re searching for a Postdoctoral Analysis Assistant for the Gene Machines’ group, led by Prof Achilles Kapanidis.

The group is well-known for creating single-molecule and single-cell fluorescence strategies (Uphoff PNAS 2013; Robb, Sci Stories 2019; Zagajewski, Nature Comm Biol 2023) and making use of them to proteins performing on DNA and RNA (Stracy, PNAS 2015; Mazumder, PNAS 2020; Mazumder, eLife 2021; El Sayyed et al Mol Cell 2024). The group not too long ago moved within the new Kavli Institute for Nanoscience Discovery (https://kavlinano.ox.ac.uk/), a vibrant atmosphere for interdisciplinary analysis on the interface of bodily and organic sciences.

The mission focuses on elucidating the mechanisms of gene transcription, by visualising the biochemical response, its kinetics, and key conformational adjustments on the single-molecule stage, and in real-time inside the crowded atmosphere of a dwelling cell. This strategy will result in new discoveries and insightful comparisons with in vitro research, and assist determine new steps for antibiotic growth.

To realize this thrilling objective, you’ll develop and apply novel single-molecule and super-resolution imaging strategies and data-analysis strategies, whereas using an interdisciplinary strategy that entails collaboration with a crew of biologists, biochemist and knowledge scientists inside the group. We’re significantly eager about experimentalists keen about microscopy and its functions to organic methods.

The perfect candidate ought to possess (or quickly receive) a doctorate in Physics, Biophysics, or associated subject, and have information of C/C++, Python, and MATLAB. Expertise in assembling, controlling and working single-molecule instrumentation and microscopes for organic research, and expertise in picture and time-series evaluation is important. Expertise with automation algorithms, LabVIEW programming, and single-molecule localization is fascinating. Expertise in cell imaging, bacterial and molecular biology, fluorescence labelling, and protein-DNA/RNA interactions is fascinating, however not required.

It’s best to have wonderful communication abilities and luxuriate in working inside an interdisciplinary group. You’ll handle tutorial and administrative actions, develop concepts for producing analysis earnings, collaborate on stories and journal articles, and have the chance to show.

Please direct enquiries to Prof Kapanidis (Achillefs.Kapanidis@physics.ox.ac.uk)

Solely functions acquired earlier than noon twenty seventh March 2024 will be thought-about. You may be required to add a press release of analysis pursuits, CV, copies of two consultant publications (or, alternatively, manuscripts in preparation) and particulars of three referees as a part of your on-line utility.

Contact Individual : recruitment Emptiness ID : 171158
Contact Telephone : Closing Date & Time : 27-Mar-2024 12:00
Pay Scale : STANDARD GRADE 7 Contact Electronic mail :
Wage (£) : £36,024 – £44,263 pa

Anticipated wage

£36024 – 44263 per yr

Location

Oxford

Job date

Sat, 17 Feb 2024 06:19:13 GMT

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