Postdoctoral Scientist in in vivo chromatin perturbation and profiling

Job title:

Postdoctoral Scientist in in vivo chromatin perturbation and profiling

Company

University of Edinburgh

Job description

Job Description:Grade UE07: £40,247 to £47,874 per annumInstitute of Genetics and Cancer / Edinburgh Cancer Research / MRC-Human Genetics Unit / School of Medicine and Veterinary MedicineFull time: 35 hours per weekFixed Term: for 12 months (Starting February 1st 2025)We are looking for an ambitious, motivated Postdoctoral researcher to join a dynamic research program discovering how chromatin regulation is altered in childhood cancer.The Opportunity:The successful candidate will work in a dynamic research group focused on understanding how altering the normal processes of chromatin and epigenetic regulation supports oncogenic gene expression programs in childhood sarcoma. You will integrate into a multi-disciplinary research environment where we seek to translate our fundamental discoveries toward the development and implementation of improved therapies for these often-underserved diseases. In this role, you will use cutting-edge genomics approaches to study the function of how essential chromatin regulatory complexes support oncogenic gene expression. Discovering important aspects of how these complexes function in cancer cells, will allow us to begin to develop novel therapeutic strategies to subvert their function(s).Your skills and attributes for success: (insert up to 5 top criteria)

  • Expertise in chromatin biology and epigenetics
  • Expertise in functional genomics
  • Expertise using in vivo experimental systems
  • Effective communication skills
  • Strong publication record

Click to view a copy of the full job description (opens new browser tab).Application InformationPlease ensure you include the following documents in your application:

  • CV
  • Cover letter detailing background and motivation

As a valued member of our team you can expect:A competitive salary.An exciting, positive, creative, challenging and rewarding place to work.To be part of a diverse and vibrant international community.Comprehensive Staff Benefits, such as a generous holiday entitlement, competitive pension schemes, staff discounts, and family-friendly initiatives. Check out the full list on our (opens in a new tab) and use our reward calculator to discover the total value of your pay and benefitsChampioning equality, diversity and inclusionThe University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our (opens new browser tab)On this occasion the University will not consider applicants requiring sponsorship for this role. International workers will therefore only be able to take up this role if they can demonstrate an alternative right to work in the UK.Key dates to noteThe closing date for applications is 19 November 2024.Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.About Us: As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.About the Team:The Cancer Research UK Edinburgh Centre brings together cancer scientists and clinicians from across the University of Edinburgh, delivering outstanding cancer research and improved patient care. With full integration of the Edinburgh Experimental Cancer Medicine Centre and the Host and Tumour Profiling Unit, our scientific and technological expertise results in new therapies being developed for patients faster.To find out more visitThe CRUK Edinburgh Centre is part of the Institute of Genetics and Cancer (IGC). This partnership with MRC Human Genetics Unit and Centre for Genomic and Experimental Medicine Centre aims to understand development and disease by using the latest developments in genetic, genomic, cellular and clinical science. The partnership provides access to state of the art scientific facilities, scientific infrastructure and business support, including on site Advanced Imaging Resource, Animal Model support, Bioinformatics Analysis Core, DNA sequencing, Flow Cytometry, Mass Spectrometry, HTPU microarray. The IGC also offers a highly collegial environment with excellent local career development support, active social, wellbeing and sustainability related groups making it a very desirable and supportive working environment.To find out more visit

Expected salary

£40247 – 47874 per year

Location

Edinburgh – Midlothian

Job date

Thu, 07 Nov 2024 05:15:52 GMT

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