Research Assistant in Protein Biochemistry and Nanomedicine

Job description

This research-focused function can be to help a Medical Analysis Council (MRC) Hole Fund challenge for designing novel multifunctional nanomedicines utilizing ferritin nanocage. This challenge goals to develop new antiviral therapeutic candidates inside one yr. The important thing goals of the challenge are to design new nanocage candidates, characterize them, and take a look at their potential antiviral exercise. The challenge will embrace elementary research to characterise and create antiviral nanocages. The antiviral exercise of nanocages can be examined in collaboration with Prof Marc Sutton at UKHSA.

We wish to make use of a motivated and passionate particular person with a level in biochemistry/cell biology or associated fields and prior expertise in immunology, virology, protein biochemistry, cell biology and/or molecular biology. The publish holder ought to have wonderful expertise in recording laboratory actions and knowledge, group, communication, and teamwork. The challenge requires collaboration with teams in the UK and throughout Europe.

The publish holder can be answerable for planning and carrying experiments to design and produce a number of proteins, their characterization, and their take a look at utilizing in vivo cell tradition assays. The publish holder will obtain trainings with totally different strategies as required and can be accountable to Dr Kourosh Ebrahimi. Our analysis group is multinational and really dynamic. We welcome people from all cultures and backgrounds. For extra details about Kourosh lab please go to  https://www.kouroshlab-kcl.com/ .

The publish holder can turn into a member of the European COST Motion (FeSImmChemNET) ( House Fesimmchemnet (fesimmchemnet-cost.com) ) led by Ebrahimi’s lab and there could also be a risk for short-term scientific mission visits (2-3 months) to a laboratory of collaborator in Europe.

In regards to the College

The College of Life Science & Drugs at King’s School London is one in every of Europe’s largest centres for biomedical analysis and instructing. The Faculty’s educational experience is globally acclaimed in a variety of primary and utilized sciences, persevering with a wealthy legacy of pioneering King’s scientists. Most of the analysis teams have been high rated within the final HEFCE Analysis Evaluation Train.

The College’s college students get pleasure from unrivalled studying alternatives, supported by sturdy partnerships with business and healthcare organisations. At each undergraduate and postgraduate stage, college students profit from the Faculty’s first-class amenities and people of its companions, together with the world-renowned accomplice NHS Trusts.

As the tutorial accomplice of selection for among the world’s main companies the College of Life Science & Drugs is shaping the way forward for healthcare by its membership of the federal government’s World Medical Excellence Cluster and its award-winning spin out corporations.

The College relies on the Man’s (London Bridge) and Waterloo Campuses. The 2 campuses are situated in shut proximity to one another on the colourful South Financial institution. The amenities for instructing and analysis on the Man’s and Waterloo Campuses have been drastically enhanced since 1998 by a capital funding programme of roughly £200 million, which has offered state-of-the-art laboratories and a high-quality studying setting.

Throughout the College, analysis divisions present the main target for the organisation of analysis exercise whereas instructing is delivered by discipline-based departments.

The Waterloo Campus gives the house for the Institute of Pharmaceutical Science, the Analytical and Environmental Sciences Division, the Diabetes and Dietary Sciences Division, and the Vascular Biology part of the Cardiovascular Division. Some points of the Institute of Pharmaceutical Science exercise are situated on the Man’s Campus. Educating is organised by the Departments of Pharmacy & Forensic Science, Vitamin and Dietetics. Specialist amenities embrace SRIF-funded Genomics and Mass Spectrometry centres, a radioisotope suite, cell tradition amenities, a Organic Companies Unit, a metabolic unit for human feeding research and high-quality library and IT provision. There are wonderful analytical amenities together with ultracentrifuge, NMR spectroscopy, HPLC, GC, GC/NIMS, GC/EIMS, GC/MS-MS, LC/MS-MS, ICP-OES and ICP-mass spectrometry gear (see additionally http://www.kcl.ac.uk/ms-facility ).

In regards to the Institute of Pharmaceutical Science

From molecules to medication

The Institute of Pharmaceutical Science (IPS) is worried with gaining an in depth understanding of the human pathological state and using this data to find, design, develop and ship medication to the affected person with a view to managing illness. It gives the multidisciplinary strategy required to contribute to the general growth of pharmacologically energetic compounds from their earliest levels of conception on the bench by their presentation as medicines, to the evaluation of their use inside the neighborhood. IPS is among the largest divisions within the well being colleges and is presently organised in 5 teams: Pharmaceutical Biophysics, Chemical Biology, Drug Supply, Pharmacology and Therapeutics, and Medical Apply and Treatment Use. There’s a vibrant PhD programme with greater than 100 college students, and a complete suite of postgraduate taught programmes.

Within the Analysis Excellence Framework 2014, based mostly on ‘energy’, an element taking into consideration the standard of the analysis output and the variety of researchers assessed, King’s School London was ranked first within the UK out of the 83 universities that made returns in Unit of Evaluation 3, to which IPS contributed.

The Institute of Pharmaceutical Science has sturdy hyperlinks with lots of the different analysis divisions at King’s School London and consequently has developed a critically essential central function within the whole analysis effort of the School. Workers have a considerable variety of collaborations at a neighborhood, nationwide and worldwide stage. Following the accreditation of King’s Well being Companions, our Tutorial Well being Sciences Centre, IPS joined three NHS belief pharmacy departments (Man’s and St Thomas’, King’s School Hospital and South London and Maudsley NHS Basis Trusts) and the Guys Medicine Analysis Unit to type the Pharmaceutical Sciences Medical Tutorial Group. The intention is to cement the collaboration between workers within the Institute and the NHS Trusts and obtain excellence in service provision, analysis, and in training and coaching.

This publish can be supplied on a fixed-term contract for 12 months till 31 July 2025.

This can be a full-time publish – 100% full time equal.

Key duties

• Analysis and scholarship. Perform experiments, analyse knowledge, attend analysis progress conferences, assist and help making ready manuscripts, collaborate with different lab members, contribute to different initiatives within the lab.
• Challenge administration. Contribute to the administration and planning of weekly experiments and analysis goal.
• Supervision of Bachelor college students.
• Contribution to normal lab duties. This consists of weekly normal lab cleansing, day by day security checks, and taking good care of devices/amenities

The above listing of duties will not be exhaustive, and the publish holder can be required to undertake such duties and duties as could fairly be anticipated inside the scope and grading of the publish.

Expertise, information, and expertise

Important standards

A Diploma in biochemistry / cell biology

Glorious expertise in recording experimental plan and knowledge.

Glorious interpersonal and networking expertise

Glorious communication expertise

Desirous to study and apply new strategies

Capability to shortly study new expertise and work independently.

Time and useful resource administration

Capability to collaborate with totally different analysis teams

Consideration to particulars

Fascinating standards

Analysis expertise in immunology

Analysis expertise in most cancers

Additional info

This publish is topic to Occupational Well being clearance.