Research Associate

Job Description

That is an thrilling alternative to hitch an internationally main interdisciplinary group of King’s School London, Oxford College and Surrey College scientists engaged on the ‘Thoughts & Pores and skin’ analysis programme.

Funded by the UK Medical Analysis Basis, we’re producing complicated sleep monitoring, mind imaging and pores and skin phenotyping information to know the mechanisms underpinning adolescent pores and skin problems. We are going to make use of machine studying, synthetic intelligence and information integration approaches to check potential hyperlinks between atopic dermatitis (AD), pruritus, sleep disturbance and altered mind perform, together with cognitive adjustments.

The bioinformatician will work below the supervision of Dr. Alessandra Vigilante, Senior Lecturer in Bioinformatics, and Professor Carsten Flohr, Chair in Dermatology and Inhabitants Well being Science and Thoughts & Pores and skin Chief Investigator and be embedded within the new KCL Hub for Utilized Bioinformatics (HAB). S/he’ll present help within the information integration analyses in addition to statistical evaluation of information. The principle goal of the function encompasses performing information integration and statistical evaluation whereas providing complete data-driven determination help by overseeing the cleansing, integration, and evaluation of numerous datasets, together with pores and skin microbiome, pores and skin immune profiles, sleep measurements, and MRI imaging. This crucially includes collaborating carefully with the interdisciplinary group to make sure the harmonization and cleanliness of a number of datasets, with the last word objective of uncovering connections between adolescent pores and skin problems, sleep disruptions, and altered mind perform within the ‘Thoughts & Pores and skin’ analysis programme.

We search for an bold candidate with established experience in bioinformatics, particularly coping with giant information units and information integration. Data of python and R are important.

Additional details about the Thoughts & Pores and skin mission is discovered right here:

https://onlinelibrary.wiley.com/doi/10.1111/all.15818

For extra details about the submit, please contact Alessandra Vigilante ( [email protected] ) and Carsten Flohr ( [email protected]) ).

In regards to the College:

King’s School London College of Life Sciences and Medication is among the largest and most profitable centres for analysis and schooling within the College. It consists of over 2000 workers and 5000 college students inside seven Faculties and two Faculties of Training.

The FoLSM Utilized Bioinformatics Hub, residence of a brand new and interdisciplinary community, is positioned on the Man’s Campus in central London. It acts as a nucleus for a vibrant analysis neighborhood spanning the complete College, bringing collectively researchers concerned in several analysis areas comparable to computational genomics, genetics, most cancers genomics, dermatology, immunology, reproductive biology and little one well being, cardiovascular analysis, neurobiology, evolutionary biology, pharmacology and others.

Hub for Utilized Bioinformatics (HAB)

https://www.kcl.ac.uk/analysis/the-hub-for-applied-bioinformatics-hab 

That is an interdisciplinary cross-cutting community that brings collectively lecturers, clinicians and workers with completely different experience and necessities, to help and undertake ground-breaking analysis involving massive information, and ship high-level education schemes. It acts as a nucleus for a vibrant analysis neighborhood, spanning the complete College of Life Science and Medication.

This submit can be supplied on a fixed-term contract for twenty-four Months.

This can be a full-time submit – 100% full time equal.

Key Tasks

• Present bioinformatics experience to assist the Thoughts & Pores and skin programme members to attain the analysis goals.
• Knowledge and statistical evaluation
• Dataset integration
• Knowledge administration
• Hold a wonderful document of study
• Put together and current information to colleagues and different scientists
• Contribute to the manufacturing of analysis experiences and publications
• The submit holder could also be requested to contribute bioinformatics experience to different tasks led by Professor Carsten Flohr.

The above listing of duties might not be exhaustive, and the submit holder can be required to undertake such duties and duties as could fairly be anticipated throughout the scope and grading of the submit.

Expertise, data, and expertise

Important standards

A PhD in Bioinformatics, Computational Biology, Biostatistics, or a associated discipline.

Demonstrated experience in dealing with and analyzing large-scale organic datasets.

Proficiency in programming languages generally utilized in bioinformatics, significantly Python and R.

Expertise with information integration methods, together with however not restricted to machine studying algorithms, synthetic intelligence strategies, and statistical approaches.

Robust statistical evaluation expertise and familiarity with related software program packages for information evaluation and visualization.

Capacity to work collaboratively in an interdisciplinary analysis surroundings, successfully speaking complicated technical ideas to non-technical group members.

Glorious problem-solving expertise and a focus to element, with the power to troubleshoot and optimize bioinformatics workflows.

Demonstrated skill to handle and prioritize a number of duties successfully.

Robust written and verbal communication expertise, evidenced by the power to jot down scientific experiences, manuscripts, and grant purposes

Fascinating standards

Earlier expertise in analyzing sleep monitoring information, mind imaging information, or microbiome and phenotypic information associated to pores and skin problems.

Data of information administration greatest practices, together with information versioning, documentation, and reproducibility.

Prior involvement in interdisciplinary analysis collaborations, significantly within the fields of dermatology, neuroscience, or sleep drugs.

Proof of unbiased analysis initiative, comparable to publications in peer-reviewed journals or contributions to open-source bioinformatics software program tasks.

* Please be aware that it is a PhD degree function however candidates who’ve submitted their thesis and are awaiting award of their PhDs can be thought of. In these circumstances the appointment can be made at Grade 5, backbone level 30 with the title of Analysis Assistant. Upon affirmation of the award of the PhD, the job title will develop into Analysis Affiliate and the wage will improve to Grade 6.