Research Associate – Genome regulation

University of Cambridge

Job title:

Analysis Affiliate – Genome regulation


College of Cambridge

Job description

The Ahringer lab within the Gurdon Institute is on the lookout for an skilled laboratory analysis scientist with experience in molecular biology and genomics to help its analysis programmes. We decipher how chromatin and gene expression are regulated to direct the step-by-step growth of the single-celled totipotent zygote to the differentiated state. We use the C. elegans mannequin, the place the invariant lineage makes it the one organism the place it’s possible to find out cell-to-cell genomic regulatory transitions throughout growth. We apply single cell profiling, bulk genomic assays, microscopy, and mutant analyses to find out how the genome is regulated to drive developmental selections and their expression.It is a key function that may provide collaborative help and technical experience throughout the scientific programmes within the laboratory. The function covers a variety of actions, permitting for continuity of lab operations. Actions embody:

  • Collaborating with lab members on analysis initiatives.
  • Offering experimental or technical help to different lab members.
  • Offering technical experience and enter to develop, optimise and troubleshoot related and novel methodologies.
  • Independently endeavor personal analysis initiatives, designing, and executing experiments in session with the group chief.
  • Taking part in educational actions, together with group conferences and journal golf equipment, seminars, and scientific conferences.
  • Writing up findings and finishing revisions.
  • Sustaining laboratory organisation, provides, and security procedures
  • Coaching new and present lab members in commonplace working procedures

It is a extremely collaborative place, so glorious communication and interpersonal abilities are important. You ought to be a motivated and organised particular person with experience in a broad vary of molecular biology methods and have the power to work each independently and as a part of a staff. Expertise in genomic profiling methods (e.g. ChIP-seq, ATAC-seq, RNA-seq, single cell analyses) is very fascinating. Candidates ought to have a PhD in a related self-discipline and have a capability to use initiative and creativity to unravel technical and organic issues.The Gurdon Institute is a world-renowned centre of Developmental biology and Most cancers analysis embedded within the College of Cambridge. It offers an distinctive and stimulating setting that promotes collaborative and interdisciplinary analysis in a supportive and trendy setting, with entry to state-of-the-art applied sciences comparable to super-resolution imaging, single-cell analyses, genome engineering, and genomics and pc modelling.Casual enquiries could be made to Julie Ahringer by way ofIn case you have any questions on this emptiness or the appliance course of, please contact .Mounted-term: The funds for this submit can be found till 31 December 2025 within the first occasion.Click on the ‘Apply’ button under to register an account with our recruitment system (when you’ve got not already) and apply on-line.Please quote reference PR41123 in your utility and in any correspondence about this emptiness.The College actively helps equality, variety and inclusion and encourages functions from all sections of society.The College has a accountability to make sure that all staff are eligible to dwell and work within the UK.Additional info

Anticipated wage

£36024 – 44263 per yr



Job date

Sat, 30 Mar 2024 07:11:39 GMT

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