Research Associate in Basement Membrane Ageing

Job title:

Research Associate in Basement Membrane Ageing

Company

University of Manchester

Job description

Applications are welcome for this 34-month, fixed-term, full-time Research Associate position in the group of Dr Alex Eckersley at the University of Manchester. We are looking for a PhD holder with experience in proteomics analysis and bioinformatics.Our group focuses on understanding the mechanisms and consequences of ageing extracellular matrix and the role of cell-signaling matrix fragments (matrikines) in tissue degeneration and repair. To this end, we pioneer and develop new proteomic mass spectrometry (MS) techniques for spatial proteomics and identifying damage modifications.You will define basement membrane damage across ageing skin, kidney and lung, and link these modifications to protease cleavage sites and oxidation-sensitive matrix protein regions. You will also identify age-dependent changes in the proteases that cleave basement membranes, determine the impact of inhibiting these enzymes on basement membrane degeneration in ageing animal models, and investigate the cell signaling potential of basement membrane matrikines.What you will get in return:

• Fantastic market leading Pension scheme
• Excellent employee health and wellbeing services including an Employee Assistance Programme
• Exceptional starting annual leave entitlement, plus bank holidays
• Additional paid closure over the Christmas period
• Local and national discounts at a range of major retailers

As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.Our University is positive about flexible working – you can find out moreHybrid working arrangements may be considered.Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.Any recruitment enquiries from recruitment agencies should be directed to .Any CV’s submitted by a recruitment agency will be considered a gift.Enquiries about the vacancy, shortlisting and interviews:Name: Dr. Alex EckersleyEmail:General enquiries:Email:Technical support:This vacancy will close for applications at midnight on the closing date.Please see the link below for the Further Particulars document which contains the person specification criteria.

Expected salary

Location

Manchester

Job date

Thu, 05 Sep 2024 04:36:05 GMT

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