Research Associate in Circadian and Sleep Neuroscience

Job title:

Research Associate in Circadian and Sleep Neuroscience

Company

University of Manchester

Job description

We seek an ambitious and motivated researcher to join our team investigating how light and circadian mechanisms interact in the brain’s supraoptic nucleus to regulate daily rhythms and timing in the sleep and wake cycles. This BBSRC funded project offers a fantastic opportunity to be at the forefront of circadian and sleep neuroscience to understand how our sleep-wake cycles are regulated by light and circadian rhythm.Working under the guidance and highly complementary expertise of Dr Mino Belle and Professor Timothy Brown, the successful candidate will apply innovative approaches for brain circuit manipulation and mapping, in and ex vivo, sophisticated machine-learning and data assimilation mathematics, with comprehensive physiological and behavioural measurements, both in mice and our powerful new day-active rodent model (Rhabdomys Pumillio). Collectively, we expect this exciting programme of work will drive a step-change in our understanding of the brain mechanisms responsible for daily and circadian control of the sleep-wake cycle and much-needed insights into how these mechanisms differ between nocturnal and diurnal mammals (like us). You will directly supervise a Research Assistant supporting these activities.The successful candidate will join a thriving neuroscience and circadian community. You will also benefit from regular interactions with members of the Time, Vision and Behaviour, an informal grouping of seven labs with common interests in light and circadian neuroscience, who share equipment and complementary skills, and the wider Centre for Biological Timing research community (https://sites.manchester.ac.uk/bio-timing/).Start date is flexible, but we hope to have someone in post by March 2025, for a period of 36 months. Applicants are expected to hold (or to shortly hold) a PhD or equivalent in a relevant branch of life sciences. Full training is available, however, the ability to work independently is essential, as is experience in and practical knowledge of neurophysiology. Experience with electrophysiological recording, preferably whole-cell patch clamp electrophysiology, and/or studies of visual or circadian function is highly desirable. Experience with laboratory rodents and relevant surgical procedures is also desirable.Successful candidates may be subject to pre-employment screening carried out on our behalf by a third party. The offer of employment will be dependent on the successful candidate passing this screening. Whilst you will be required to provide express consent at a later stage, by continuing with your application now you acknowledge that you are aware that such screening will take place and agree to take part in the process.What you will get in return:

• Fantastic market leading Pension scheme
• Excellent employee health and wellbeing services including an Employee Assistance Programme
• Exceptional starting annual leave entitlement, plus bank holidays
• Additional paid closure over the Christmas period
• Local and national discounts at a range of major retailers

As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.Our University is positive about flexible working – you can find out moreHybrid working arrangements may be considered.Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.Any recruitment enquiries from recruitment agencies should be directed to .Any CV’s submitted by a recruitment agency will be considered a gift.Enquiries about the vacancy, shortlisting and interviews:Name: Dr Mino BelleEmail:General enquiries:Email:Technical support:This vacancy will close for applications at midnight on the closing date.Please see the link below for the Further Particulars document which contains the person specification criteria.

Expected salary

Location

Manchester

Job date

Sat, 08 Feb 2025 02:17:22 GMT

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