Research Associate in Enzyme Design and Engineering (3 posts available)

University of Manchester

Job title:

Analysis Affiliate in Enzyme Design and Engineering (3 posts accessible)


College of Manchester

Job description

‘Design and Engineering of Proteins with an Expanded Amino Acid Alphabet’Positions can be found for 3 Postdoctoral Analysis Associates with expertise in directed evolution, biocatalysis, biochemistry or a associated self-discipline. The intention of the analysis is to develop new practical proteins constructed from an expanded set of amino acids and strategies for his or her manufacturing. This place relies within the Manchester Institute of Biotechnology (MIB) beneath the ssupervision of Prof Anthony Inexperienced and Dr Sarah Lovelock.Nature makes use of twenty canonical amino acids to provide proteins with various constructions and features. Nevertheless, these amino acids include restricted chemical range, proscribing our capability to engineer proteins with new features and fascinating properties. On this challenge we develop environment friendly strategies for selectively introducing non-canonical amino acids with new practical facet chains into proteins. These strategies will likely be optimized to permit economical manufacturing of proteins constructed utilizing an expanded genetic code. We’ll subsequently capitalize on these new practical amino acids to develop enzymes in proteins with new features.This can be a extremely interdisciplinary challenge on the reducing fringe of enzyme engineering analysis and the profitable applicant could have full entry to state-of-the-art services for high-throughput and automatic enzyme engineering, together with liquid dealing with robots, colony pickers and a collection of excessive throughput analytical services. The profitable candidate could have the chance to use and additional develop their experience in each elementary and translational science, that are extremely related to a future profession within the pharmaceutical and wider chemical business.Candidates ought to have, or count on to realize a PhD or equal, in Chemical Biology, Biochemistry or Biocatalysis, and have a thesis submitted previous to taking over the place. We search functions from skilled researchers with a confirmed monitor document in biocatalyst optimization utilizing directed evolution, and enzyme characterization. You need to be able to working beneath your personal initiative but additionally collaborating with industrial and tutorial analysis companions, so wonderful communication and organisational expertise are required.The College of Chemistry is strongly dedicated to selling equality and variety, together with the Athena SWAN Constitution for gender equality in increased training. The College holds a Silver Award which recognises their good follow in relation to gender; together with versatile working preparations, family-friendly insurance policies, and assist to permit employees to realize an excellent work-life stability. We significantly welcome functions from girls for this submit. Appointment will all the time be made on benefit. For additional info, please go to positively welcome functions from girls, who’re at the moment under-represented at this grade. Appointment will likely be made on benefit.The College will actively foster a tradition of inclusion and variety and can search to realize true equality of alternative for all members of its group.What you’ll get in return:

  • Improbable market main Pension scheme
  • Wonderful worker well being and wellbeing companies together with an Worker Help Programme
  • Distinctive beginning annual depart entitlement, plus financial institution holidays
  • Extra paid closure over the Christmas interval
  • Native and nationwide reductions at a spread of main retailers

As an equal alternatives employer we welcome candidates from all sections of the group no matter age, intercourse, gender (or gender identification), ethnicity, incapacity, sexual orientation and transgender standing. All appointments are made on benefit.Our College is constructive about versatile working – you could find out extraHybrid working preparations could also be thought-about.Please be aware that we’re unable to answer enquiries, settle for CVs or functions from Recruitment Businesses.Any recruitment enquiries from recruitment businesses needs to be directed to .Any CV’s submitted by a recruitment company will likely be thought-about a present.Enquiries concerning the emptiness, shortlisting and interviews:Title: Anthony Inexperienced or Sarah LovelockElectronic mail: or Electronic mail:Normal enquiries:Electronic mail:Technical assist:This emptiness will shut for functions at midnight on the deadline.Please see the hyperlink beneath for the Additional Particulars doc which accommodates the particular person specification standards.

Anticipated wage



Job date

Wed, 27 Mar 2024 05:58:30 GMT

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