University of Manchester
Job title:
Research Associate in Synthetic Glycosylated Nanomaterials
Company
University of Manchester
Job description
The postholder will work as a Postdoctoral Research Associate in the group of Prof Matthew Ian Gibson in the Department of Chemistry at the University of Manchester. For more information about the Gibson group and their research interests, please visit the group website (https://www.gibsongroupresearch.com). This role is focussed on developing and growing the teams research base in using, and targeting, glycans for diagnostics and biosensors, based upon nanoparticle platforms. For example, the team developed one of the first COVID-19 rapid diagnostics tools which was evaluated with clinical samples. ACS Central Science, 2020, 6, 11, 2046. Key to this is the use of polymeric tethers to capture analytics and other ligands.The GibsonGroup has world-class facilities based in both the Department of Chemistry (where this role is primarily based) and also in the Manchester Institute of Biotechnology (MIB). The Chemistry laboratories are brand new (2023) featuring dedicated write up space, fume hoods, and analytical equipment including UV-Vis, FTIR (and in 2024) NMR spectrometers, microscopes and liquid handling systems. For polymer analysis we have a multidetector SEC suite, as well as the departments core NMR and Mass Spec facilities. We access the UKs National Materials Institute, the Royce, which is in an adjacent building. In the MIB we have dedicated tissue culture and microbiology laboratories and a bioanalytical suite including biolayer interferometry, flow cytometry, high-content live cell microscopy and (in 2024) confocal microscopy. From 2025 the team will host a UK unique automated glycan synthesis platform.The GibsonGroup is a positive research environment, and the successful candidate is expected to contribute to the groups research culture, focussed on team work.The project will involve the synthesis and characterization of advanced glycosylated, or glycan-targeting materials and measurement of their interactions with biological targets. This will involve a range of controlled polymerization techniques, particularly RAFT. There will also be significant (bio) analytical measurements undertaken to include biolayer interferometry, for which the team has its own dedicated platform. The PDRA will report directly to Professor Matthew I. Gibson. A strong research and publication track record is essential with demonstrated ability to lead and finish (including publishing) projects. You must have excellent communication, presentation, interpersonal and teamworking skills.As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit.Our University is positive about flexible working – you can find out moreBlended working arrangements may be consideredPlease note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies.Enquiries about the vacancy, shortlisting and interviews:Name: Professor Matthew I. GibsonEmail:General enquiries:Email:Technical support:Jobtrain: 0161 850 2004This vacancy will close for applications at midnight on the closing date.Please see the link below for the Further Particulars document which contains the person specification criteria.
Expected salary
Location
Manchester
Job date
Fri, 26 Jul 2024 00:26:56 GMT
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