This is an exciting opportunity to join the group of Kristine Arnvig at UCL’s department of structural and molecular biology, part of the UCL Division of Biosciences. The project aims to resolve the role of riboswitch-regulation of glycine metabolism in different pathogenic mycobacteria including Mycobacterium tuberculosis.
About the Role
To be an active member of a research project/team assisting in the development of research proposals and the planning and delivery of research into riboswitch regulation of glycine metabolism in pathogenic mycobacteria. The project revolves around the general microbiology and metabolomics of glycine metabolism and the central role of glycine riboswitches. For this role, the successful candidate will have to plan their own day-to day activities and experiments, analyse data and present results. Experiments include working in the CL3 lab, RNA isolation, RNA-sequencing and its analysis, other RNA related techniques including, but not limited to, inline and structure probing, reporter gene assays, general microbiology and metabolomics. Experiments will include isotope work and you will need to undergo local training for CL3 work and for handling radioactive isotopes.
This is an open-ended contract with funding available for 36 months in the first instance. Please note that the role is not eligible for hybrid working due to the nature of the research.
Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Grade 6B (salary £35,702 – £37,548 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD Thesis.
A job description and person specification can be accessed at the bottom of this page.
If you have any queries about the role, please contact Dr Kristine Arnvig. If you need reasonable adjustments or a more accessible format to apply for this job online or have any queries about the application process, please contact Biosciences staffing.
You are a highly motivated and independent scientist, who can provide original contributions to the subject areas of RNA biology, riboswitches and metabolism in pathogenic mycobacteria. You have (or are about to obtain) a PhD in one of the relevant subject areas and a proven track record of working with pathogenic mycobacteria, RNA, transcriptomic analysis or bacterial metabolisms and metabolomics.
You will assist the team in the development, planning and delivery of research funded by the Medical Research Council (MRC) and will be expected to produce independent and original contributions to the investigations of riboswitch regulation in mycobacteria. In addition to developing and conducting the research, you will also communicate results as scientific papers and in scientific presentations at conferences.
What we offer
As well as the exciting opportunities this role presents, we also offer some great benefits. please visit https://www.ucl.ac.uk/work-at-ucl/reward-and-benefits to find out more.
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