Research Fellow

Job title:

Analysis Fellow

Firm

UCL

Job description

About usThe Division of Neuromuscular Illnesses is a hub for scientific and analysis excellence throughout the spectrum of spinal wire and neuromuscular illnesses. Our group of world-leading scientific, genetic and primary science researchers focus their work on understanding the causes and organic mechanisms resulting in Neuromuscular Illness and translating this data into growing novel therapeutic options that’s of direct profit to neurological issues corresponding to motor neurone illness, Alzheimer’s illness and neuromuscular illness.The Patani Lab, based mostly within the Division, goals to grasp the molecular and mobile mechanisms underpinning motor neuron illness (ALS). We use a wide range of affected person derived iPSC traces to analyze disease-related occasions at molecular stage throughout completely different related cell sorts, together with motor neurons, astrocytes and microglia.In regards to the positionWe’re looking for a Analysis Fellow to affix our established and devoted staff of researchers utilizing human induced pluripotent stem cells to check Motor Neuron Illness (ALS).Based mostly within the laboratory of Professor Rickie Patani, you can be engaged on resolving the molecular foundation of motor neuron degeneration with a selected deal with the connection between genomic instability and aberrant RNA metabolism utilizing established human stem cell fashions of ALS. You’ll utilise cutting-edge sequencing approaches, corresponding to DRIP-seq, INDUCE-seq and bulk RNAseq (by a collaboration with the Boulton lab on the Francis Crick Institute) to discover the advanced useful interplay between these processes.It is a compelling alternative to contribute to ground-breaking, high-impact analysis initiatives inside an intellectually stimulating, globally various scientific group.The position is on the market instantly and funded by My Identify’5 Doddie Basis for 2 years within the first occasion.About youYou should have a PhD in a related topic, vital expertise in mathematical modelling of organic information and in utilizing R/Python and/or different programming languages. Expertise of superior molecular biology strategies, analysing bulk RNAseq datasets, with particular deal with splicing and RNA processing can be required for this job.UCL welcomes functions from worldwide candidates who require a visa.What we provideBeginning wage supplied within the rage £42,099 – £49,263 each year.Appointment as Analysis Fellow relies upon having been awarded a PhD; if this isn’t the case, preliminary appointment shall be as Analysis Assistant (wage £37,332 – £39,980 each year) with appointment as Analysis Fellow being backdated to the date of ultimate submission of the PhD thesis.In addition to the thrilling alternatives this position presents, we additionally supply some nice advantages; go to to seek out out extra.Our dedication to Equality, Range and InclusionAs London’s International College, we all know range fosters creativity and innovation, and we wish our group to symbolize the range of the world’s expertise. 12% of Institute workers are actively engaged on EDI initiatives; go to for extra details about what we’re doing. We subsequently significantly encourage functions from candidates who’re more likely to be underrepresented in UCL’s workforce; these embrace folks from Black, Asian and ethnic minority backgrounds, disabled folks, LGBTQI+ and gender various folks in all roles, and girls in Grade 9 and 10 roles.

Anticipated wage

£42099 – 49263 per 12 months

Location

London

Job date

Sat, 06 Apr 2024 06:47:11 GMT

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