Research Fellow – Biomedical Devices

Job title:

Research Fellow – Biomedical Devices

Company

University College London

Job description

About usThe UCL Centre for Biomaterials in Surgical Reconstruction and Regeneration, led by Professor Song, collaborates with scientists, clinicians and industry partners to develop biomedical and engineering innovation. These include 3D models of soft and hard tissue, targeted cell and gene therapy delivery systems, and nanotechnology-based devices, such as hyperplastic nanofiber-guided human iPSC-derived muscle and neuromuscular junction models, piezoelectric nanofiber acoustic devices, and wearable/implantable biosensors.Further information about the Centre can be found .About the roleApplications are invited for a postdoctoral research fellow to join the Song laboratory ( ) at UCL Centre of Biomaterials for Surgical Reconstruction and Regeneration.This is a new exciting role funded by a multi-center 5-year MRC and MNDA programme grant to discern the effects of Amyotrophic lateral sclerosis (ALS)/Fronto-temporal dementia (FTD) mutations on human neuron intrinsic and synaptic properties as well as neural network function.The successful candidate will design and fabricate neuromuscular junction model devices, and work together with multi-disciplinary teams to tackle the mechanism of ALS/FTD neurodegenerative diseases.This role is for a qualified and experienced scientist/engineer who has been working in an academic or commercial research laboratory/company related to biomedical devices for muscle/neuron sensing, neuromuscular junction, neuron/muscle tissue/disease modelling and drug discovery. We design and fabricate synthetic scaffolds, biosensors and integrate with a human iPSC-based neuromuscular co-culture system and apply this system to investigate the cause of human ALS/FTD conditions, and lead to novel therapeutic targets.The post holder will contribute to the plan to deliver technical innovation and lead specified work packages of developing human iPSC-based neuromuscular junction model systems and ALS/FTD disease models in collaboration with other teams at UCL and KCL. To ensure successful development of the cellular model device and facilitate multidisciplinary collaborators to progress towards understanding the cause of ALS/FTD conditions, the candidate requires a strong background/knowledge of design, fabrication and integration of polymeric nanofiber-based devices, muscle/neuronal cell-culture devices and muscle/neuron detectors. Experience in polymer synthesis and process, electrospinning technique, neuron/muscle tissue engineering, cell culture and characterization is also desirable. In addition, they also require excellent interpersonal skills to work within and across diverse and interdisciplinary teams.Appointment Details:

• This post is graded at grade 7, the annual salary for which ranges from £43,374 to £48,007 (including London Allowance).
• This is a fixed-term post for 24 months in the first instance

Application Details:

• The advert will close on 6 May 2025 at 23:59 GMT, however we may close applications early if we receive a high volume of applications. Early application submission is recommended.
• Interview Date(s) TBC
• If you have any queries about the role, please contact Prof. Wenhui Song at
• If you need reasonable adjustments or a more accessible format to apply for this job online or have any queries about the application process, please contact the HR Team on l.oppong@ucl.ac.uk
• The UCL Ways of Working supports colleagues to be successful and happy at UCL through sharing expectations around how we work.

About youThe post holder will have the following:

• The post holder must have a PhD degree in polymer science and engineering, chemistry, biomaterials, tissue engineering, bioengineering, chemical engineering, neuron cell/muscle culture devices, high throughput medical sensors/devices or in a relevant discipline or equivalent professional experience.
• Expertise in design, fabrication and integration of electrospun-nanofibre-based devices, tissue/disease model devices, point-of-care medical devices, organ-on-a-chips, neuronal cell multi-electrode array devices, conducting polymer-based sensors and devices.
• Experience in polymer synthesis and process, fabrication of multi-electrode array devices and electrospinning technique is also desirable.
• The successful holder must have scientific rigor and excellent analytical and synthetic capabilities with proven ability and commitment to carry out high quality original research.
• Experience in muscle/neuron tissue engineering, neurodegenerative disease modelling, and cell culture and characterization would be an advantage.

What we offerAs well as the exciting opportunities this role presents, we also offer some great benefits some of which are below:

• 41 Days holiday (including 27 days annual leave 8 bank holiday and 6 closure days)
• Defined benefit career average revalued earnings pension scheme (CARE)
• Cycle to work scheme and season ticket loan
• On-Site nursery
• On-site gym
• Enhanced maternity, paternity and adoption pay
• Employee assistance programme: Staff Support Service
• Discounted medical insurance

The full range of staff benefits can be found .Our commitment to Equality, Diversity and InclusionAs London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce. These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women.You can read more about our commitment to Equality, Diversity and Inclusion .Available documents

Expected salary

£43374 – 48007 per year

Location

North West London

Job date

Sun, 13 Apr 2025 02:13:40 GMT

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