Research Fellow in Cancer Evolution

Job title:

Research Fellow in Cancer Evolution

Company

University of Surrey

Job description

The University of Surrey is a global community of ideas and people, dedicated to life-changing education and research.We are ambitious and have a bold vision of what we want to achieve – shaping ourselves into one of the best universities in the world, which we are achieving through the talents and endeavour of every employee.Our culture empowers people to achieve this aim and to collectively, and individually, make a real difference.The roleWe are seeking a Postdoctoral Research Fellow for a (up-to) 3-year position to work on an exciting project funded by the Medical Research Council and led by Dr Bingxin Lu.This project aims to reconstruct the evolutionary dynamics of chromosomal instability in cancer genomes. Understanding how chromosomal instability evolves during the progression from precancerous lesions to malignancy, metastasis, and treatment resistance is important for cancer detection and treatment. Building upon our previously published method, CNETML ( ), this project will develop more realistic evolutionary models of copy number alterations and better phylogenetic inference methods with wider applicability. The developed methods will then be applied to extensive publicly available datasets to investigate the dynamics of chromosomal instability. Our new methods will enhance the toolkit for cancer researchers and drive broader applications of cancer phylogenetic inference. The insights gained from the inferences will also support personalized therapy and advance public health efforts.The successful candidate will not only design and conduct the research but also write and communicate results as scientific papers and in scientific presentations at national and international conferences.About youThe successful candidate will have a strong research background and should have a PhD (or close to completion) in computational biology, bioinformatics, computer science, or related fields that include a substantial amount of computing and mathematical/statistical modelling, ideally related to phylogenetic method development. Working knowledge in genomics, evolutionary biology, cancer biology, or population genetics is desirable. Experience in programming is essential.How to applyPlease submit your cover letter, CV, and contact of three references with your application on the University of Surrey Website.For informal inquiries, please contact Dr Bingxin Lu .The University of Surrey reserves the right to close this vacancy early based on Volume and Calibre of applications.Further details

Expected salary

£37174 – 39355 per year

Location

Guildford, Surrey

Job date

Fri, 21 Mar 2025 05:50:56 GMT

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